Results 21 to 30 of about 835,253 (311)
Biological activity and cellular uptake of [Ru(eta(5)-C5H5)(PPh3)(Me(2)bpy)][CF3SO3] complex [PDF]
, 2013 Anticancer activity of the new [Ru(eta(5)-C5H5)(PPh3)(Me(2)bpy)][CF3SO3] (Me(2)bpy = 4,4'-dimethyl-2,2'-bipyridine) complex was evaluated in vitro against several human cancer cell lines, namely A2780, A2780CisR, HT29, MCF7, MDAMB231 and PC3. Remarkably,
Côrte-Real, Leonor +6 more
core +1 more source
Doxorubicin-Loaded Human Serum Albumin Submicron Particles: Preparation, Characterization and In Vitro Cellular Uptake [PDF]
, 2020 Doxorubicin (DOX) is an effective anthracycline antibiotic drug which is commonly used in a broad range cancer therapy. However, due to dose depending side effects and toxicity to non-cancerous tissues, its clinical applications are restricted.
Bäumler, Hans +7 more
core +1 more source
Pharmaceuticals, 2021 Albumin is one of the most important proteins in human blood. Among its multiple functions, drug binding is crucial in terms of drug distribution in human body.
Małgorzata Maciążek-Jurczyk +8 more
doaj +1 more source
Heliyon, 2017 Aims: The present study to address one of the mechanisms in preeclampsia, examined whether levels of oxidative stress, human serum albumin, and endothelial function correlate in pregnant women and whether human serum albumin reduces levels of superoxide ...
Hiroyuki Kinoshita +8 more
doaj +1 more source
A Comprehensive Spectroscopic Analysis of the Ibuprofen Binding with Human Serum Albumin, Part II
Scientia Pharmaceutica, 2021 Human serum albumin (HSA) is the most abundant human plasma protein. HSA plays a crucial role in many binding endos- and exogenous substances, which affects their pharmacological effect.
Anna Ploch-Jankowska +2 more
doaj +1 more source
Interaction of anticancer reduced Schiff base coumarin derivatives with human serum albumin investigated by fluorescence quenching and molecular modeling [PDF]
, 2014 The specific binding of five reduced Schiff base derived 7-amino-coumarin compounds with antitumor activity to human serum albumin, the principal binding protein of blood, was studied by fluorescence spectroscopy.
Belatika +48 more
core +2 more sources
Serum albumin and osmolality inhibit Bdellovibrio bacteriovorus predation in human serum [PDF]
, 2017 We evaluated the bactericidal activity of Bdellovibrio bacteriovorus, strain HD100, within blood sera against bacterial strains commonly associated with bacteremic infections, including E. coli, Klebsiella pneumoniae and Salmonella enterica.
A Chonn +45 more
core +1 more source
Photoprogramming Allostery in Human Serum Albumin [PDF]
Bioconjugate Chemistry, 2018 Developing strategies to interfere with allosteric interactions in proteins not only promises to deepen our understanding of vital cellular processes but also allows their regulation using external triggers. Light is particularly attractive as a trigger being spatiotemporally selective and compatible with the physiological environment.
Rindia M. Putri +8 more
openaire +3 more sources
Fungicide Tebuconazole Influences the Structure of Human Serum Albumin Molecule
Molecules, 2019 Studies of interactions between pesticides and target mammalian proteins are important steps toward understanding the pesticide′s toxicity. Using calorimetric and spectroscopic methods, the interaction between triazole fungicide tebuconazole and ...
Katarína Želonková +5 more
doaj +1 more source
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2022 The aim: to highlight the main points of albumin synthesis, posttranslational modifications and functions in normal conditions and in patients with liver cirrhosis.Key points. Albumin is the most abundant protein in blood plasma.
A. A. Turkina +3 more
doaj +1 more source