Iron‐induced lipid peroxidation of phosphatidylethanolamine (PE) species is the key driver of ferroptosis. The authors discovered that PHOSPHO1 lowers the level of PE in retinal pigment epithelial cells thus reducing the formation of lipid peroxides. Lowering PE levels can also prevent the creation of autolysosomes, reduce the production of free iron ...
Zhiyang Chen+19 more
wiley +1 more source
Prognostic values of serum alkaline phosphatase and globulin levels in patients undergoing intravenous thrombolysis. [PDF]
Zhu HJ+8 more
europepmc +1 more source
A near‐infrared organic room temperature phosphorescence probe of fibroblast‐activation protein in liver cancer microenvironment is prepared to accurately locate liver cancer and determine surgical margins, aiming at guiding hepatectomy and achieving accurate liver cancer resection.
Jinghua Li+11 more
wiley +1 more source
Association between serum alkaline phosphatase and bacteraemia in haemodialysis outpatients: a multicentre retrospective cross-sectional study. [PDF]
Katasako A+7 more
europepmc +1 more source
Mesenteric thrombosis: An unusual complication of severe acute pancreatitis—Report of two cases
Abstract The incidence of acute pancreatitis is 34 per 100 000 people in the general population and is on the rise. Approximately 15% to 20% of all patients experience severe pancreatitis, with a mortality rate nearing 20%. This condition is often linked to vascular complications, although mesenteric thrombosis is a rare presentation.
Asya Zubillaga‐Mares+5 more
wiley +1 more source
Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu+11 more
wiley +1 more source
Elevated Levels of Serum Alkaline Phosphatase are Associated with Increased Risk of Cardiovascular Disease: A Prospective Cohort Study. [PDF]
Liu K+16 more
europepmc +1 more source
Early diagnosis and prognosis prediction of central nervous system infections are critical. This study introduces a deep‐learning model utilizing cerebrospinal fluid immune‐cell morphology captured via 3D holotomography. The model effectively predicts infection etiology and prognosis, achieving high accuracy.
Bo Kyu Choi+5 more
wiley +1 more source
Elevated serum alkaline phosphatase correlates with postoperative cognitive dysfunction: A retrospective cohort study based on STROBE statement. [PDF]
Li X+5 more
europepmc +1 more source