Results 131 to 140 of about 5,257,522 (337)
Siliao yanjiu, 2021 The experiment studied the effect of mixed storage of elephant grass and sugarcane tail on fermentation quality of silage and the effect of silage on the apparent digestibility, lactation performance and serum biochemical index of buffalo.
Li-juan PENG +7 more
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 1911 Mode of access: Internet.Issued by the Columbia university biochemical ...
Columbia University. Biochemical association.
core
Siliao yanjiu, 2023 The aim of the experiment was to investigate the effect of dietary mushroom residue on growth performance, nutrient apparent digestibility and serum biochemical indexes of weaned piglets.
KUANG Dan, ZHOU Hao
doaj
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Interactions Between Genetic Variants in Glucose Transporter Type 9 (SLC2A9) and Dietary Habits in Serum Uric Acid Regulation [PDF]
, 2010 Aim To investigate possible interactions between genetic variants in glucose transporter type 9 (SLC2A9) gene and dietary habits in serum uric acid regulation.
Klišmanić, Zorana +11 more
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Siliao yanjiu, 2022 The experiment was to study the effect of self-made full price mixed pellet feed with molasses on growth performance, serum biochemical indexes and benefit of fattening mutton sheep.
Bing-lian YAN, Xiao-yan WEI, Xiao-yan LI
doaj
To assess weather the external application of traditional Chinese medicine can promote the trabecular bone regeneration and callus fibrous transformation by regulating IL-1, BMP2, TNF-α, TGF and other serum biochemical index AKP. [PDF]
, 2023 ZHOU Xi-jiang +5 more
openalex +1 more source