Results 141 to 150 of about 5,257,522 (337)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Effects of Atractylodes extract on growth performance， serum biochemical index， and intestinal barrier health in early-weaned piglets

Siliao yanjiu
The study aimed to explore the effect of Atractylodes extract on growth performance, serum biochemical index and intestinal barrier health in early-weaned piglets.
CHEN Bo, WANG Huan-huan, YANG Xue-xi, CHEN Lin, TAO An-xin, WANG Ya-man, LI Meng-yu, GAO Yang   +7 more
doaj  

Effect of dietary addition of fermented apple dregs on production performance and serum biochemical index of fattening pigs

Siliao yanjiu, 2021
Effect of fermented apple drees on performance and serum indexes of finishing pigs were studied. 100 fattening pigs were divided into five groups with 20 fattening pigs in each group.
Zi-hui ZHAO, Bo-xiang CHEN, Yuan-xin LI, Wei-wei CHENG, Ming YANG, Hui-lin GUO   +5 more
doaj  

Effects of Replacing Fish Meal with Stickwater Hydrolysate and Meal on the Growth, Serum Biochemical Indexes, and Muscle Quality of Yellow Catfish (Tachysurus fulvidraco) [PDF]

, 2023
Shuang Zheng, Yong Shi, Junzhi Zhang, Jihong Dai, Yi Hu, Lei Zhong   +5 more
openalex   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Serum and urine biochemical parameters.

, 2015
Serum and urine biochemical parameters in all groups.
Yaning Zheng (785245), Wenhan Huang (785246), Feifeng Ren (785248), Lin Tang (65412), Ling Zhang (18071), Ruyu Yan (785247), Lei Luo (284798)   +6 more
core   +1 more source

Effects of compound Chinese herbal medicine on serum biochemical indexes， immune， and antioxidant function in perinatal dairy cows

Siliao yanjiu
The experiment aimed to investigate the effects of compound Chinese herbal medicine on serum biochemical indexes, immune, and antioxidant function in perinatal dairy cows.
ZHANG Zhe, HAN Xuesong, HAN Jiahao, BAO Yadong, LIU Yongjun, WANG Yu   +5 more
doaj  

Effects of fermented feed on growth performance, serum biochemical indexes, antioxidant capacity, and intestinal health of lion-head goslings [PDF]

, 2023
Zhiqi Fu, Na Ao, Xiaoen Liang, Jinhuang Chen, Yuchuan Wang, Qing Wang, Jing Fu, Chunpeng Liu, Lizhi Lu   +8 more
openalex   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Effects of dietary energy on growth performance, carcass characteristics, serum biochemical index, and meat quality of female Hu lambs. [PDF]

Anim Nutr, 2020
Wang Y, Wang Q, Dai C, Li J, Huang P, Li Y, Ding X, Huang J, Hussain T, Yang H.   +9 more
europepmc   +1 more source