Results 81 to 90 of about 5,257,522 (337)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Serum antioxidants as predictors of the adult respiratory distress syndrome in septic patients [PDF]
, 1993 Adult respiratory distress syndrome (ARDS) can develop as a complication of various disorders, including sepsis, but it has not been possible to identify which of the patients at risk will develop this serious disorder.
Moore, Frederick A. +9 more
core +1 more source
Siliao yanjiu, 2023 The experiment was to study the effect of Piper sarmentosum extract (PSE) on growth performance, immune organ index, immune globulin, serum biochemical indices and antioxidant function of chicks.
CHANG Ye +5 more
doaj
International Journal of Poultry Science, 2011 A study was carried out to determine the effect of crude protein level in diets on Serum Biochemical Indexes and Gastrointestinal Micro flora of yellow quails. Four diets with different crude protein levels 17.75%, 19.95%, 21.85%, 24.08% were used to feed 192 yellow quails during 50-day-old to 95-day-old in this experiment.
Y.X. Li +4 more
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei. [PDF]
, 2014 Closely related African trypanosomes cause lethal diseases but display distinct host ranges. Specifically, Trypanosoma brucei brucei causes nagana in livestock but fails to infect humans, while Trypanosoma brucei gambiense and Trypanosoma brucei ...
Currier, Rachel B. +18 more
core +1 more source
Siliao yanjiu, 2021 The experiment was to study the effect of compound microbial additives on growth performance, serum biochemical index and immune function of weaned piglets.
Rui-sheng LIU +7 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source