Results 181 to 190 of about 464,832 (264)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Effects of Modified Corn Straw Dietary Fiber on Growth Performance, Nutrient Metabolism, Serum Biochemistry, Antioxidant Capacity, and Hepatic Lipid Deposition in Broiler. [PDF]

Animals (Basel)
Qin Y, Si B, Qi X, Zhu Z, Liu C, Chang J, Wang L, Jin S, Li X, Yuan L, Yin Q, Wang Z, Wang P.   +12 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Age-related changes in growth and fecal parameters, nutrient digestibility, hematology, and serum biochemistry of Beagle dogs. [PDF]

J Anim Sci Technol
Kang Y, Kim Y, Cho JH, Kim HB, Ahn J, Kim MK, Song M, Kyoung H.   +7 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Effects of Bacillus amyloliquefaciens F1 postbiotics on growth performance, serum biochemistry, intestinal morphology and intestinal microbiota of yellow-feathered broilers. [PDF]

Poult Sci
Chen W, Li W, Xu Y, Huang Y, Lin C, Luo W, Luo C, Zhang H, Yan X.   +8 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Hematology and serum biochemistry reference intervals for the common opossum Didelphis marsupialis. [PDF]

Vet Res Commun
Ceballos CP, Aristizábal-Parra E, Castillo-Vanegas VE.   +2 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Transport stress alters serum biochemistry and gut microbiota in Tibetan sheep (ovis aries): a 30-day recovery assessment. [PDF]

BMC Microbiol
Wang R, Wang M, Wang J, Wang P, Ou J, Tang W, Sun G, Wang Q, Cheng X, Huang Y, Chen J, Zhang Z, Ren C.   +12 more
europepmc   +1 more source