Results 81 to 90 of about 442,299 (263)
Urinary steroid profiling in diagnostic evaluation of an unusual adrenal mass
Endocrinology, Diabetes & Metabolism Case Reports, 2019 Adrenal oncocytomas are rare tumours, with only approximately 160 cases reported in the literature. We report the use of urinary steroid profiling as part of their diagnostic evaluation and prognostication.
N F Lenders, J R Greenfield
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Acute and chronic toxicity studies of hydromethanol leaf extract of Helianthus annuus Linn. in rats
Asian Pacific Journal of Tropical Medicine, 2018 Objective: To investigate the safety levels of hydromethanol leaf extract of Helianthus annuus Linn. (H. annuus) in rat. Methods: Acute oral toxicity test of hydromethanol leaf extract of H.
Samuel O Onoja +3 more
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Türk Biyokimya DergisiThe aim of this study was to evaluate the effects of five different brands of gel separator biochemistry serum tubes (BD-Vacutainer, Greiner Bio One-Vacuette, Samplix, Pirmax and Ayset) on routine biochemistry test measurement results performed with both
Balci Tevfik +7 more
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Association Between Serum Irisin Levels and ST-Segment Elevation Myocardial Infarction
International Journal of General Medicine, 2023 Derya Ozturk,1 Adem Melekoglu,1 Ertugrul Altinbilek,1 Mustafa Calik,2 Arzu Kosem,3 Hakan Kilci,4 Naile Fevziye Misirlioglu,5 Hafize Uzun6 1Sisli Hamidiye Etfal Education and Research Hospital, Department of Emergency, İstanbul, Turkey ...
Ozturk D +7 more
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Serum biochemistry alterations in canine leptospirosis
, 1990 Serim biochemistry abnormalities were studied in naturally occuring leptospirosis in dogs in order to establish an useful profile for diagnostic purpose. The dogs were grouped according to clinical manifestations. Group I was comprised by 65 uremic and icteric dogs, reagents to serovar copenhagem and/or icterohaemorrhagiae and the second group by 15 ...
Kogika, Marcia Mery +2 more
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source