Results 51 to 60 of about 13,679 (178)

Silencing the Signal: The Metastasis Suppressor NDRG1 Disrupts Small Extracellular Vesicle‐Mediated Crosstalk in Pancreatic Cancer

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
NDRG1 suppresses pancreatic cancer progression by disrupting small extracellular vesicle biogenesis, altering cargo composition, and inhibiting EV uptake by cancer cells—thereby impairing tumour–stroma communication and fibrotic activation. This study reveals NDRG1 as a novel regulator of extracellular vesicle dynamics and a promising therapeutic ...
Jiawei Chang, Shafi Alenizi, Heloisa Zaccaron Milioli, Winston Lay, Saranya Pounraj, Yujie Li, Mekonnen Sisay Shiferaw, Elham Hosseini‐Beheshti, Zaklina Kovacevic   +8 more
wiley   +1 more source

Wilson's disease patients with normal ceruloplasmin levels

The Turkish Journal of Pediatrics, 1999
Wilson's disease, an inborn defect of copper metabolism, is a fatal disease unless specific treatment is given. Hepatic presentation mimics almost all kinds of liver disease and the diagnosis is sometimes problematic.
Aysel Yüce, Nurten Koçak, Hasan Özen, Figen Gürakan   +3 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Assessment of Serum Copper, Ceruloplasmin, Copper:Ceruloplasmin ratio in Pregnant women in and around of Warangal [PDF]

Perspectives In Medical Research, 2017
Background: Copper is an essential micronutrient and has an important role in foetal development. Disorders of Copper and Ceruloplasmin levels has been associated with pathological pregnancies.The determination of Copper:Ceruloplasmin ratio has been ...
Pullaiah Akinepalli 1 , Narender Gaddam 2
doaj  

Aceruloplasminemia: a rare disease - diagnosis and treatment of two cases

Revista Brasileira de Hematologia e Hemoterapia, 2011
Aceruloplasminemia is a rare autosomal recessive disease in which a mutation leads to the absence or dysfunction of ceruloplasmin. Deficiency of this enzyme leads to the accumulation of iron in various organs; aceruloplasminemia is usually characterized ...
Maria do Rosário Ferraz Roberti, Handel Meireles Borges Filho, Cláudio Humberto Gonçalves, Flávio Leão Lima   +3 more
doaj   +1 more source

Associations Between Comorbidities, Developmental Status, and Disease Severity in Children With Autism Spectrum Disorder: A Multicenter Cross‐Sectional Study in China

Autism Research, Volume 19, Issue 6, June 2026.
ABSTRACT Children with autism spectrum disorder (ASD) frequently present with co‐occurring conditions that can influence autism symptom severity and complicate clinical management. However, studies with clinician‐confirmed diagnoses in non‐Western populations remain limited.
Dizhou Pang, Guiqin Duan, Qing Shang, Huichun Zhang, Binbin Wang, Huaili Ding, Huihui Kang, Yue Zhao, Yuxia Lu, Gai Tian, Li Zhang, Wu Jiang, Ganyu Wang, Cailing Liang, Lingling Zhang, Bingbing Li, Zhenghua Li, Chunlan Song, Yanyan Yang, Yazhe Wang, Kaichen Yue, Yongbin Lang, Jiatian Liu, Xiaoli Zhang, Yiran Xu, Changlian Zhu   +25 more
wiley   +1 more source

Comparative Analysis of Serum Ceruloplasmin Levels in Wilson Disease by Conventional Enzymatic Assay and Immunologic Method

Siriraj Medical Journal, 2006
Objective: Serum ceruloplasmin, which has markedly decreased in 95% of patients with Wilson disease, is one of the most useful markers in the diagnosis of this genetic disease.
Rungtip Soi-ampornkul, Sarawut Junnu, Wattanachai Chotinaiwattarakul, Uchanee Wongmanee, Bhoom Suktitipat, Neelobol Neungton   +5 more
doaj  

Serum and Red Blood Cell Antioxidant Status in Patients with Bronchial Asthma

Canadian Respiratory Journal, 2000
Levels of vitamin C, ceruloplasmin, transferrin and albumin in serum, and glutathione in red blood cells were investigated in 40 patients with asthma to determine whether their antioxidant status was different from healthy subjects.
Hüseyin Vural, Kürsat Uzun
doaj   +1 more source

Copper and ceruloplasmin concentrations in the blood serum oe schizophrenic patients

Arquivos de Neuro-Psiquiatria, 1968
The serum copper (26 cases) and ceruloplasmin (20 cases) are studied in 45 patients with schizophrenia. The following conclusions were drawn from this study: 1) the blood copper is significantly higher in patients with schizophrenia; 2) the variations of
Luis Marques-Assis, Francisco Bastos De Jorge   +1 more
doaj   +1 more source

The effects of ACTH and of cortisol on serum ceruloplasmin in rabbits [PDF]

FEBS Letters, 1971
Ceruloplasmin, a copper containing blue colored protein (molecular weight 160,000), has moderate amounts of oxidase activity towards a variety of polyamines and polyphenols [l] . It has been known for quite some time that estrogen in the form of ethinyl estradiol [2] or stilbestrol [3] causes a marked increase in serum copper levels (which reflects ...
openaire   +2 more sources