Results 151 to 160 of about 34,612 (242)

Switching Patients With Congenital Adrenal Hyperplasia to Modified‐Release Hydrocortisone Capsules: Relative Bioavailability and Disease Control

Clinical Endocrinology, EarlyView.
ABSTRACT Background Replacement therapy with modified‐release hydrocortisone capsules (MRHC) restores the physiological circadian cortisol rhythm in congenital adrenal hyperplasia (CAH). Aims To determine the relative bioavailability of MRHC and evaluate an optimal protocol to switch CAH patients from standard therapy to MRHC.
Richard John M. Ross, Wiebke Arlt, Aude Brac de la Perriere, Angelica Lindén Hirschberg, Anders Juul, Deborah P. Merke, John D. C. Newell‐Price, Alessandro Prete, D. Aled Rees, Nicole Reisch, Monica Stikkelbroeck, Philippe A. Touraine, Kerry Maltby, Jo Quirke, Helen Coope, John Porter   +15 more
wiley   +1 more source

Characterizing the plasma protein binding profiles of chemistry diversified antisense oligonucleotides in human and mouse plasma using an ultrafiltration method. [PDF]

Front Pharmacol
Yun C, Fukami K, Shinkyo R, Jiang RR.
europepmc   +1 more source

The association of cycle threshold value with clinical features in patients infected with Omicron variant. [PDF]

Virus Res
Yang W, Tao T, Zhang J, Yao Y, Chen M, Liu M, Wu M, Lei W.   +7 more
europepmc   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

The association between serum albumin-globulin ratio and overactive bladder in American adults: a cross-sectional study. [PDF]

Eur J Med Res
Du YZ, Liu JH, Zheng FC, Zhou Q, Guo J.
europepmc   +1 more source

Quantitative proteomics identifies plasma protein alterations that associate with metabolic and thrombotic profile changes after bariatric surgery

Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2647-2657, May 2025.
Abstract Objective Roux‐en‐Y gastric bypass (RYGB) surgery has been shown to lead to favourable health outcomes in obese patients. However, the molecular changes that occur and how they relate to clinical measures are poorly understood. Here, we characterise the proteomic alterations that occur in plasma of RYGB patients before and 9 months after ...
Hasnain Ahmed, Marco F. Fernandes, Kazim Abbas, Silvia A. Synowsky, Sally L. Shirran, Ramzi A. Ajjan, Alan J. Stewart   +6 more
wiley   +1 more source

The Effectiveness of Levamisole and Broccoli in Lead Poisoning: Hematobiochemical Changes and Tissue Damage in the Liver, Kidney, and Spleen of Wistar Rats. [PDF]

J Toxicol
Shahbazi K, Raeeszadeh M, Akradi L.
europepmc   +1 more source

Impact of sirolimus on long‐term adverse cardiovascular outcomes in kidney transplant recipients: A nationwide cohort study

European Journal of Clinical Investigation, EarlyView.
The findings demonstrated no significant difference in MACE between the sirolimus‐treated and untreated groups (hazard ratio, 1.40; 95% confidence interval, .77–2.55), despite a higher incidence of dyslipidaemia in the sirolimus‐treated group. However, subgroup analysis indicated an increased MACE risk in KTRs with pre‐transplant congestive heart ...
Jinhyun Park, Wonhui Choi, Jinseub Hwang, Ha Young Jang, Yun Kim, Young‐Mi Ah, Jin‐Won Kwon, Kyung Hee Choi, Yun‐Kyoung Song   +8 more
wiley   +1 more source

Key biomarkers in type 2 diabetes patients: A systematic review. [PDF]

Diabetes Obes Metab
Le TN, Bright R, Truong VK, Li J, Juneja R, Vasilev K.   +5 more
europepmc   +1 more source

The impact of immature granulocytes on the outcome of patients with decompensated cirrhosis

European Journal of Clinical Investigation, EarlyView.
Immature granulocyte (IG) count and percentage had a predictive role in patients with decompensated cirrhosis, making them an objective and easily available marker of prognosis for this group of patients. In addition, IG percentage was the only factor independently associated with transplant‐free survival.
Magdalini Adamantou, Dimitrios Glaros, Evangelinos Michelis, Apostolos Papageorgiou, Eleni Adamopoulou, Antonia Alevizou, Menelaos Athanasiadis, Eleni Pergantina, Vasiliki E. Georgakopoulou, Vasileios Lekakis, Evangelos Cholongitas   +10 more
wiley   +1 more source