Results 71 to 80 of about 10,721,542 (345)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
From Manual to Intelligent: A Review of Input Data Preparation Methods for Geographic Modeling
ISPRS International Journal of Geo-Information, 2019 One of the key concerns in geographic modeling is the preparation of input data that are sufficient and appropriate for models. This requires considerable time, effort, and expertise since geographic models and their application contexts are complex and ...
Zhi-Wei Hou +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A Simulation-Based Optimization Approach for Reliability-Aware Service Composition in Edge Computing
IEEE Access, 2020 With the prevalence of Internet of Things (IoT), edge computing has emerged as a novel computing model for optimizing traditional cloud computing systems by moving part of the computational tasks to the edge of the network for better performance and ...
Jiwei Huang, Jingyu Liang, Sikandar Ali
doaj +1 more source
Context constraint integration and validation in dynamic web service compositions [PDF]
, 2010 System architectures that cross organisational boundaries are usually implemented based on Web service technologies due to their inherent interoperability benets.
Pahl, Claus +2 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Dynamic integration of context model constraints in web service processes [PDF]
, 2009 Autonomic Web service composition has been a challenging topic for some years. The context in which composition takes places determines essential aspects. A context model can provide meaningful composition information for services process composition. An
Bandara, Kosala Yapa +2 more
core
Mathematical Services Composition
Electronic Notes in Theoretical Computer Science, 2005 AbstractThis paper describes the definition and the use of a plan language in the context of mathematical web services. A plan is a document intended to describe how to use different mathematical web services to solve a particular problem. A plan is like a program in which most of the function calls have to be handled by web services.
Chicha, Yannis, Gaëtano, Marc
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Energy-Efficient Composition of Configurable Internet of Things Services
IEEE Access, 2017 Along with the adaptation of Internet of Things (IoT) to support various industrial applications, the cooperation and coordination of smart things is a promising strategy for satisfying requirements that are beyond the capacity of any single smart thing.
Mengyu Sun +4 more
doaj +1 more source