Results 81 to 90 of about 285,311 (268)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

An Improved Evolutionary Method for Social Internet of Things Service Provisioning Based on Community Detection

IEEE Access
Social IoT (SIoT) refers to socializing in the Internet of Things (IoT), where things generate social relationships. Due to the development of objects and issues such as delayed response, slow search, and composite service process, distributed object ...
Bahar Allakaram Tawfeeq, Amir Masoud Rahmani, Abbas Koochari, Nima Jafari Navimipour   +3 more
doaj   +1 more source

Formal Analysis of Trust and Reputation for Service Composition in IoT. [PDF]

Sensors (Basel), 2023
Ahmed AIA, Hamid SHA, Gani A, Abdelaziz A, Abaker M.   +4 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Data-intensive service deployment based on edge computing

Dianxin kexue, 2019
The demand is getting higher and higher for data processing due to big data volume, thus, data-intensive service shave emerged. When solving complex problems, multiple data-intensive services are often united as a service portfolio.
Yongmei GAO, Guanjie CHENG
doaj  

Correctness of services and their composition

, 2010
Wir studieren die Korrektheit von Services und Servicekompositionen und untersuchen, wie der Entwurf von korrekten Servicekompositionen systematisch unterstützt werden kann. Wir legen dabei den Fokus auf das Kommunikationsprotokoll der Services. Mithilfe von formalen Methoden tragen wir zu drei Szenarien von SOC bei.
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Alloy-based verification of Web service composition

Tongxin xuebao, 2012
Service composition was the core problem of service computing,the validity and reliability of service composition had become the premise of service execution.A method was presented which utilizes the finite state machine (FSM)to model the business ...
Jiu-xin CAO, Jiang-lin WU, Guo-jin WANG, Bo LIU, Peng-wei YANG, Dan DONG   +5 more
doaj  

An Optimization Method Based on Be-ACO Algorithm in Service Composition Context. [PDF]

Comput Intell Neurosci, 2022
Du Z, Miao H.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source