Results 81 to 90 of about 7,060,908 (299)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Software Reliability in Semantic Web Service Composition Applications [PDF]
Web Service Composition allows the development of easily reconfigurable applications that can be quickly adapted to business changes. Due to the shift in paradigm from traditional systems, new approaches are needed in order to evaluate the reliability of
Andreea DIOSTEANU, Liviu Adrian COTFAS
core
An Optimization Algorithm for Service Composition Based on an Improved FOA
Tsinghua Science and Technology, 2015 Large-scale service composition has become an important research topic in Service-Oriented Computing (SOC). Quality of Service (QoS) has been mostly applied to represent nonfunctional properties of web services and to differentiate those with the same ...
Yiwen Zhang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Approach to Web Services Composition [PDF]
, 2016 The paper presents an approach to the composition of web services based on their meta descriptions. The process of web services sequence formation is depicted. Such web services sequence describes execution of certain user’s task. The method of user’s tasks scenario formation is proposed that allows to define dynamically an ordered sequence of web ...
Alexander V. Koval +2 more
openaire +3 more sources
, 2010 In the S-Cube research framework, the Service Composition and Co-ordination (SCC) layer encompasses the functions required for the aggregation of multiple services into a single composite service offering, with the execution of the constituent services ...
Rosenberg, Florian +6 more
core +4 more sources
MR-IDPSO: A Novel Algorithm for Large-Scale Dynamic Service Composition
Tsinghua Science and Technology, 2015 In the era of big data, data intensive applications have posed new challenges to the field of service composition. How to select the optimal composited service from thousands of functionally equivalent services but different Quality of Service (QoS ...
Yanping Zhang, Zihui Jing, Yiwen Zhang
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Distribution pattern-driven development of service architectures [PDF]
, 2009 Distributed systems are being constructed by composing a number of discrete components. This practice is particularly prevalent within the Web service domain in the form of service process orchestration and choreography.
Barrett,Ronan +3 more
core +2 more sources