Results 71 to 80 of about 4,707,888 (270)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

A Novel UX-Centered ITSM Framework for Technology Startups: Beyond Traditional Service Management

open access: yesJournal of Information Systems and Informatics
This research explores the integration of User Experience (UX) principles into IT Service Management (ITSM) frameworks within resource-constrained B2B SaaS technology startups.
Marcel Marcel, Tubagus Ahmad Marzuqi
doaj   +1 more source

Cultural Change of Applying User Involvement for Improving Healthcare Quality: A Review of the Impact on Attitudes, Values and Assumptions among Healthcare Professionals and Users

open access: yesKvalita Inovácia Prosperita, 2017
Purpose: The purpose of this study is to provide a review of the impact on culture (attitudes, values and assumptions) among both healthcare professionals, as well as users, when involving users for improving quality in healthcare. Methodology/Approach:
Jonas Boström   +2 more
doaj   +1 more source

INCLUSIVE APPROACH OUTCOMES IN DEVELOPMENT PROJECTS FOR CULTURAL AND LINGUISTIC MINORITIES – AN INTERVIEW STUDY [PDF]

open access: yesPsychiatria Fennica, 2023
A Finnish initiative called TUULI project, led by the Finnish Institute for Health and Welfare, was launched in 2019 to respond to the need of providing accessible psychoeducational material for newly arrived refugees and for professionals working ...
Niina Porta   +3 more
doaj  

Sustainable Value Proposition Design in a Product-Service System [PDF]

open access: yes, 2012
Many companies have started to add services to their tangible products in order to defend themselves from increased competition from low-cost economies.
Kristofer Nygren, Niclas Österlind
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Can we plan services for children in foster care? Or do we just have to cope with what comes through the door?

open access: yesSocial Work and Society, 2017
To what extent is it possible to plan ahead for children coming into care? How can we ensure that there are enough foster homes available for new entrants and that the range of facilities is sufficiently wide to meet all of their different needs?
Roger Bullock
doaj   +2 more sources

SOA Services Identification and Design Methods From Business Models: A Systematic Literature Review

open access: yesIEEE Access
Modern organizations are process-oriented. To remain competitive in the digital transformation era, these organizations design and implement Information Systems (IS) to support their business processes. The emergence of the Service-Oriented Architecture (
Redouane Blal   +5 more
doaj   +1 more source

Integrating web services into data intensive web sites [PDF]

open access: yes, 2004
Designing web sites is a complex task. Ad-hoc rapid prototyping easily leads to unsatisfactory results, e.g. poor maintainability and extensibility.
Domingue, John   +2 more
core  

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