Results 71 to 80 of about 15,544,913 (349)

Near-infrared responsive polycaprolactone coatings for magnesium implants: Photodynamic antibacterial and controllable dissolution

Journal of Magnesium and Alloys
Magnesium implants have received widespread attention in orthopaedic surgery. However, the mechanical degradation and concurrent inflammation caused by the rapid corrosion of Mg limits their applications.
Xi Liu, Jinglong Pan, You Lv, Xu Wang, Xiaoze Ma, Xinxin Zhang, Guangyi Cai, Zehua Dong   +7 more
doaj   +1 more source

What went right and what went wrong in my cellar door visit? A worldwide analysis of TripAdvisor’s reviews of Wineries & Vineyards

Wine Economics and Policy, 2022
The purpose of this work is to study the issues of service quality and service failure during visits to cellar doors in the five regions where wine tourism is most developed: Hunter Valley (AU), Mendoza (AR), Napa Valley (the USA), Stellenbosch (ZA), and
Elena Barbierato, Iacopo Bernetti, Irene Capecchi   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Adaptive Servo‐Ventilation for Glottic Closure in a Patient With Adult‐Onset Congenital Central Hypoventilation Syndrome: A Case Report

Respirology Case Reports
Congenital central hypoventilation syndrome (CCHS) is a rare disorder characterised by autonomic dysfunction and typically presents in infancy, although adult‐onset disease is increasingly recognised. We report a genetically confirmed case of adult‐onset
Sushil Agwan, Saul McWhae, Krishna Bajee Sriram   +2 more
doaj   +1 more source

Impacto de una intervención educativa estructurada en las actitudes y la práctica de la insuficiencia cardiaca en Latinoamérica

Archivos de Cardiología de México
Objetivo: La implementación de las guías de insuficiencia cardiaca (IC) en la práctica real rara vez es adecuada y la mayoría de los pacientes no reciben tratamientos óptimos.
Lucrecia M. Burgos, María P. Duczynski, María L. Coronel, Jorge Thierer   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Endothelial biomarkers (Von willebrand factor, BDCA3, urokinase) as predictors of mortality in COVID-19 patients: cohort study

BMC Pulmonary Medicine
Background SARS-CoV-2 is a systemic disease that affects endothelial function and leads to coagulation disorders, increasing the risk of mortality.
Rocío Nayeli Sánchez-Santillán, Martha Patricia Sierra-Vargas, Dulce González-Islas, Octavio Gamaliel Aztatzi-Aguilar, Rogelio Pérez-Padilla, Arturo Orea-Tejeda, Yazmín Debray-García, Manolo Ortega-Romero, Candace Keirns-Davis, Alejandra Loaeza-Roman, Alejandra Rios-Pereda   +10 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Clinical service organisation for heart failure [PDF]

, 2000
Chronic heart failure (CHF) is a serious, common condition associated with frequent hospitalisation. Several different disease management interventions (clinical service organisation interventions) for patients with CHF have been proposed.To assess the effectiveness of disease management interventions for patients with CHF.We searched: Cochrane CENTRAL
S, Taylor, J, Bestall, S, Cotter, M, Falshaw, S, Hood, S, Parsons, L, Wood, M, Underwood   +7 more
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source