Results 41 to 50 of about 191,071 (260)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Service function chaining for mission critical services
ITU Journal on Future and Evolving TechnologiesServices in critical missions, such as firefighting, have demanding service level agreements. The functions of such services must be deployed and managed according to the status and needs of the missions. The proposed Mission Critical Service Function Chaining (MSC-SFC) introduces an architecture relying on Software-Defined Networking (SDN), Service ...
Bruno Sousa +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Online Parallelized Service Function Chain Orchestration in Data Center Networks
IEEE Access, 2019 In recent years, much attention has been focused on deploying service function chains (SFCs), each of which is composed of a set of virtual network functions (VNFs) in a specified order.
Gang Sun +4 more
doaj +1 more source
Availability and Reliability of Service Function Chain: A Quantitative Evaluation View
International Journal of Computational Intelligence Systems, 2023 Service function chain (SFC) based on network function virtualization (NFV) technology can handle network traffic flexibly and efficiently. The virtual network function (VNF), as the core function unit of SFC, can experience software aging, which reduces
Yaru Li +5 more
doaj +1 more source
Traffic Steering for Service Function Chaining [PDF]
IEEE Communications Surveys & Tutorials, 2019 Dynamic service function chaining (SFC) is a technique that facilitates the enforcement of advanced services and differentiated traffic forwarding policies. It dynamically steers the traffic through an ordered list of service functions. Enabling SFC capabilities in the context of a software defined networking (SDN) architecture is promising, as it ...
Hantouti, Hajar +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Energy-Efficient Service Function Chain Provisioning [PDF]
Electronic Notes in Discrete Mathematics, 2018 Network Function Virtualization (NFV) is a promising network architecture concept to reduce operational costs. In legacy networks, network functions, such as firewall or TCP optimization, are performed by specific hardware. In networks enabling NFV coupled with the Software Defined Network (SDN) paradigm, network functions can be implemented ...
Huin, Nicolas +3 more
openaire +4 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source