Results 61 to 70 of about 323,296 (258)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Distributed, asynchronous algorithms for network control with contracted flow rates – a review

Journal of Telecommunications and Information Technology, 2006
The paper reviews current algorithms for distributed, asynchronous control of networks when the customer is guaranteed to get some predetermined (e.g., as a part of a service level agreement – SLA) values of flow.
Andrzej Karbowski
doaj   +1 more source

A three-stage heuristic task scheduling for optimizing the service level agreement satisfaction in device-edge-cloud cooperative computing. [PDF]

PeerJ Comput Sci, 2022
Sang Y, Cheng J, Wang B, Chen M.
europepmc   +1 more source

Service Level Agreements

Revue pro právo a technologie, 2011
Předmětem  příspěvku  je  vymezení  tzv.  Service  Level Agreements,  tedy  servisních  smluv  pro  plnění  posky-tovaná  v  oblasti  ICT.  Úvodem  příspěvku  je  SLA  defi-nována a jsou vymezeny její základní typy. V další části jsou  pak  uvedeny  základní  obsahové  náležitosti  SLA z hlediska jejich praktického užití.
Šurmanová, Michaela, Knebl, Ondřej
openaire   +1 more source

D2.2.3: Service Level Agreements

, 2011
Service Level Agreements (SLAs) are of fundamental value for all organisations that provide services to users. SLAs record a common understanding about services, priorities, responsibilities, guarantees, and warranties of the services provided. This is very important not only for the organisations but also for the users to allow them to know the type ...
Delimoges, Arnaud, Moussier, Pascal, Bela Dias, Ana, Merida, Carlos, Bernardi, Sergio, Prangov, Georgi, Kwiecien, Agnieszka   +6 more
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

ZSM Framework for Autonomous Security Service Level Agreement Life-Cycle Management in B5G Networks

Future Internet
In the rapidly evolving landscape of telecommunications, the integration of commercial 5G solutions and the rise of edge computing have reshaped service delivery, emphasizing the customization of requirements through network slices.
Rodrigo Asensio-Garriga, Alejandro Molina Zarca, Jordi Ortiz, Ana Hermosilla, Hugo Ramón Pascual, Antonio Pastor, Antonio Skarmeta   +6 more
doaj   +1 more source

Internet of Things for Mental Health: Open Issues in Data Acquisition, Self-Organization, Service Level Agreement, and Identity Management. [PDF]

Int J Environ Res Public Health, 2021
Gutierrez LJ, Rabbani K, Ajayi OJ, Gebresilassie SK, Rafferty J, Castro LA, Banos O.   +6 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source