Results 121 to 130 of about 58,076 (334)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Civil and Environmental Engineering, 2015 Qualitative characteristics of pavement in wide range reflects the pavement serviceability, which is a summary of the characteristics of the pavement, providing a fast, smooth, economical and especially safe driving of motor-vehicles.
Slabej Martin +4 more
doaj +1 more source
Orbit Selection for the Proposed Lynx Observatory Mission [PDF]
The Advanced Concepts Office design team performed several analyses and trades in support of orbit selection for the proposed Lynx mission, an x-ray observatory being submitted to the Astro2020 Decadal Survey.
Baysinger, M. +8 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Evaluation of floor vibrations induced by walking in reinforced concrete buildings
, 2013 Floor vibrations induced by human walking were investigated in a reinforced concrete structure. Six experimental floor structures were built in laboratories with the same dimensions and boundary conditions.
Griffin, M.J. +2 more
core
Experimental methodology on the serviceability behaviour of reinforced ultra‐high performance fibre reinforced concrete tensile elements [PDF]
, 2020 Majid Khorami +2 more
openalex +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
LandAssessing urban green spaces’ (UGSs) serviceability is crucial for ecosystems and well-being, but traditional approaches focus only on the quantity of UGSs while neglecting their spatial configuration or depend on region-specific data sources ...
Yuetong Qin +4 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source