Results 81 to 90 of about 1,480,356 (245)

An architecture for autonomic web service process planning [PDF]

, 2008
Web service composition is a technology that has received considerable attention in the last number of years. Languages and tools to aid in the process of creating composite web services have been received specific attention.
Moore, Colm, Pahl, Claus, Wang, MingXue
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Supporting Dynamic Service Composition at Runtime based on End-user Requirements [PDF]

, 2009
Network-based software application services are receiving a lot of attention in recent years, as observed in developments as Internet of Services, Software as a Service and Cloud Computing.
Ferreira Pires, Luis, Silva, Eduardo, Sinderen, Marten van   +2 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Cloud Service Composition Based on Multi-Granularity Clustering

Journal of Algorithms & Computational Technology, 2014
With the popularity of cloud computing, how to meet user's personalized and diverse requirements of service composition is a key problem that needs to be resolved.
Huihui Cai, Lizhen Cui
doaj   +1 more source

Enhancing Service Composition by Discovering Cloud Services Community

IEEE Access, 2019
In the cloud service community, cloud service providers typically limit component cloud services to perform a specific and limited function to maximize the versatility of cloud services.
Shiting Wen, Jinqiu Yang, Genlang Chen, Jianwen Tao, Xinjie Yu, An Liu   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A Survey on Service Composition Middleware in Pervasive Environments [PDF]

, 2009
The development of pervasive computing has put the light on a challenging problem: how to dynamically compose services in heterogeneous and highly changing environments? We propose a survey that defines the service composition as a sequence of four steps:
Ibrahim, Noha, Le Mouel, Frederic
core   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

A Framework for Design and Composition of Semantic Web Services [PDF]

, 2004
Semantic Web Services (SWS) are Web Services (WS) whose description is semantically enhanced with markup languages (e.g., OWL-S). This semantic description will enable external agents and programs to discover, compose and invoke SWSs.
González-Cabero, R., Gómez-Pérez, A., Lama, M.   +2 more
core   +2 more sources