Results 81 to 90 of about 6,440,715 (300)

SLA based cloud service composition using genetic algorithm

IJAIN (International Journal of Advances in Intelligent Informatics), 2016
Cloud computing tends to provide high quality on-demand services to the users. Numerous services are evolving today. Functionally similar services are having different non-functional properties such as reliability, availability, accessibility, response ...
N Sasikaladevi
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Service Solution Planning Considering Priori Knowledge and Fast Retrieval

IEEE Access, 2018
Service composition is widely used to build complex value-added composite services to meet various coarse-grained requirements of customers. Discovering relevant services as the constituents of composite services is a crucial task, which needs to be ...
Ruilin Liu, Xiaofei Xu, Zhongjie Wang, Quan Z. Sheng   +3 more
doaj   +1 more source

The Approach to Web Services Composition [PDF]

, 2016
The paper presents an approach to the composition of web services based on their meta descriptions. The process of web services sequence formation is depicted. Such web services sequence describes execution of certain user’s task. The method of user’s tasks scenario formation is proposed that allows to define dynamically an ordered sequence of web ...
Alexander V. Koval, Larisa S. Globa, Rina Novogrudska   +2 more
openaire   +3 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Improving Semantic Web Services Composition Performance, Using Data Mining Techniques

Journal of Algorithms & Computational Technology, 2010
There are many usages for the Web services in the World Wide Web. For creating new services we can compose other developed services in the way we want to use them.
Shahab Bayati, Ardeshir Bahreininejad, Ali Farahmand Nejad, Ssdegh Kharazmi   +3 more
doaj   +1 more source

Correctness of services and their composition

, 2010
Wir studieren die Korrektheit von Services und Servicekompositionen und untersuchen, wie der Entwurf von korrekten Servicekompositionen systematisch unterstützt werden kann. Wir legen dabei den Fokus auf das Kommunikationsprotokoll der Services. Mithilfe von formalen Methoden tragen wir zu drei Szenarien von SOC bei.
openaire   +3 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source