Results 121 to 130 of about 61,366 (284)
The return of metabolism: biochemistry and physiology of glycolysis
Biological Reviews, EarlyView.ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Contact Dermatitis, EarlyView.Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez +29 more
wiley +1 more source
Genetic Insights Into Allergic Contact Dermatitis: Reassessing the Role of LCE3C_LCE3B Deletion
Contact Dermatitis, EarlyView.This study found no significant association between the LCE3C_LCE3B deletion and allergic contact dermatitis or polysensitisation in Tunisian patients, suggesting that other genetic or environmental factors may contribute to disease susceptibility. ABSTRACT Background Allergic contact dermatitis (ACD) is a multifactorial inflammatory skin disorder ...
Zeineb Ben Lamine +10 more
wiley +1 more source
The FEBS Journal, EarlyView.We have converted the only known true bacterial monoterpene synthase, cineole synthase from Streptomyces clavuligerus (bCinS, C10 substrate), to a highly competent sesquiterpene synthase (C15) with a minimum number of rational mutations. By comparison with diterpene synthases (C20), we were then able to bestow diterpene synthase activity on bCinS. This
Nicole G. H. Leferink +3 more
wiley +1 more source
Copaiba Oil–Resin Reduces the Alveolar Bone Damage Triggered by Apical Periodontitis in Rats
International Endodontic Journal, EarlyView.ABSTRACT Aim This study aimed to investigate the effects of copaiba oil–resin on induced apical periodontitis in rats. Methodology A total of 24 male Wistar rats were divided equally into three groups (eight animals each): control (C), apical periodontitis (AP) and apical periodontitis with copaiba administration (AP + COP).
Rayssa Maitê Farias Nazário +11 more
wiley +1 more source
Journal of Diabetes Investigation, EarlyView.ABSTRACT Background Inflammation plays an essential role in the pathogenesis of diabetic nephropathy (DN). Linderalactone (LNL), as a natural sesquiterpene lactone, has been discovered to have anti‐inflammatory activation. However, the effects of linderalactone on diabetes‐associated renal damage remain unclear.
Hao Chen +7 more
wiley +1 more source
Structural variation drives rhizome innovation and adaptive divergence in sister Medicago species
Journal of Integrative Plant Biology, EarlyView.Chromosome‐scale genome analysis, population resequencing, stress‐responsive transcriptomes and functional assays showed that coding and regulatory structural variants, especially gene duplications and noncoding presence‐absence variants, underlie rhizome formation in alpine Medicago archiducis‐nicolai and contrasting xeric adaptation in its non ...
Hongyin Hu +14 more
wiley +1 more source
Antiprotozoal activity of flavonoids from Eupatorium arnottianum [PDF]
, 2017 Dichloromethane and ethanol extracts of Eupatorium arnottianum were evaluated for invitroleishmanicidal activity. The dichloromethane extract produced 80% and 85% of growthinhibition on both Leishmania mexicana and Leishmania amazonensis promastigotes ...
Cazorla, Silvia Ines +7 more
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Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context
Journal of Integrative Plant Biology, EarlyView.Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac +15 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Tanshinones, the major bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used to treat cardiovascular and cerebrovascular diseases. While jasmonates (JAs) are known to modulate tanshinones accumulation, the molecular link between JA signalling and tanshinone biosynthesis remains unclear.
Renjun Qu +9 more
wiley +1 more source