Results 161 to 170 of about 92,534 (385)

Emerging Anti-Mitotic Activities and Other Bioactivities of Sesquiterpene Compounds upon Human Cells

open access: yesMolecules, 2017
We review the bio-activities of natural product sesquiterpenes and present the first description of their effects upon mitosis. This type of biological effect upon cells is unexpected because sesquiterpenes are believed to inactivate proteins through ...
A. Bosco, R. Golsteyn
semanticscholar   +1 more source

Characterization of the Cubamyces Menziesii Terpenome

open access: yesChemBioChem, EarlyView.
The genome of Cubamyces menziesii reveals 18 putative sesquiterpene cyclase genes. These genes are cloned and expressed in Escherichia coli, yielding 10 active enzymes. Using farnesyl diphosphate as substrate, the enzymes are analyzed, and the products characterized after bioconversion, uncovering diverse sesquiterpene structures. This study highlights
Létitia Leydet   +10 more
wiley   +1 more source

A review of the anticancer effects of sesquiterpene nerolidol on different malignant conditions [PDF]

open access: yesJournal of Medicinal Plants
Background: Nerolidol (NER) is a sesquiterpene alcohol with various biological ‎and pharmacological activities, especially antitumor effects against different cancer models. The ‎anticancer properties of NER‎ are reportedly mediated by increased reactive
Ameneh Mohammadi   +5 more
doaj  

Genome Mining Reveals a Novel Nephthenol‐Producing Diterpene Synthase from the Sandfly Lutzomyia Longipalpis

open access: yesChemBioChem, EarlyView.
The discovery of a terpene synthase of insect origin that makes the apparently cryptic product nephthenol from geranylgeranyl diphosphate sheds light on hidden biosynthetic potential. Populations of the sandfly, Lutzomyia longipalpis, use the diterpene sobralene as a sex/aggregation pheromone, which is likely produced in the insect through the activity
Charles Ducker   +6 more
wiley   +1 more source

Untersuchungen in der Sesquiterpen‐Reihe [PDF]

open access: yesBerichte der deutschen chemischen Gesellschaft, 1909
n ...
openaire   +3 more sources

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas   +5 more
wiley   +1 more source

Toward a Cannabis Terroir: Untargeted Metabolomic Profiling of Authentic Samples Using Gas Chromatography–High‐Resolution Mass Spectrometry (GC‐HRMS) and Liquid Chromatography–High‐Resolution Tandem Mass Spectrometry (LC‐HRMS/MS)

open access: yesDrug Testing and Analysis, EarlyView.
This study developed a comprehensive metabolomics workflow using GC‐HRMS and LC‐HRMS/MS and analyzed 35 CBD‐type cannabis flowers grown under varying conditions. Key discriminative compounds enabled classification by chemical phenotype and cultivation environment. The results showed that environmental factors influence chemical profiles, supporting the
Sandra N. Poetzsch   +3 more
wiley   +1 more source

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