Results 81 to 90 of about 92,534 (385)

Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]

open access: yes, 2016
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D.   +2 more
core   +2 more sources

Cytotoxic Compounds Isolated from Murraya tetramera Huang

open access: yesMolecules, 2014
A new compound and seven known compounds were isolated from Murraya tetramera Huang for the first time, and they were identified with NMR and MS spectral analysis. It was confirmed that the new compound was 10-methoxy-7-methyl-2H-benzo[g]chromen-2-one (3)
Chun-Xue You   +9 more
doaj   +1 more source

Sesquiterpenes from the Fungus Antrodiella albocinnamomea with Cytotoxicity and Antibacterial Activity

open access: yesJournal of Fungi, 2023
Eight new sesquiterpenes, namely, albocinnamins A−H (1−8), along with two known ones (9 and 10), have been isolated from the fungus Antrodiella albocinnamomea.
Jinlei Ning   +4 more
doaj   +1 more source

Catalytic Plasticity of Germacrene A Oxidase Underlies Sesquiterpene Lactone Diversification1[OPEN]

open access: yesPlant Physiology, 2019
The striking catalytic plasticity of germacrene A oxidase, an evolutionary conserved enzyme in the Asteraceae, has led to the existence of diverse sesquiterpene lactones, including artemisinin.
Trinh-Don Nguyen   +4 more
semanticscholar   +1 more source

Sesquiterpenes in Cereals and Spices

open access: yes, 2019
This chapter provides an in-depth overview of the sesquiterpenes found in cereals and spices. These aliments provide an important source of nutrients for our health, and they are consumed daily. Thus, a knowledge of the constituents is vital to understand the origin of their benefits for human health as well as the possible side effects that can arise ...
Marcos Cárdenas, David   +4 more
openaire   +3 more sources

A Short Synthesis of Bisabolane Sesquiterpenes [PDF]

open access: yesMolecules, 2011
A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials.
Du, Zhen-Ting   +3 more
openaire   +4 more sources

Effects of phenoxyartemisinin derivatives on the inhibition of colorectal cancer and cancer stem cells

open access: yesBulletin of the Korean Chemical Society, EarlyView.
In this study, we investigate the anticancer properties of phenoxyatemisinin (4) among acetal‐type artemisinin derivatives by evaluating their growth inhibitory effects on colon cancer cells and CSCs. Given their established role as potent antimalarial agents and their emerging potential in oncology, artemisinin‐based compounds offer a promising avenue
Nam Hyun Kim   +3 more
wiley   +1 more source

Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]

open access: yes, 2013
Key Points First report demonstrating in vivo elimination of multiple LIC populations from childhood ALL cases using animal models. In vivo models of leukemia are essential for drug evaluation studies.
Blair, Allison   +3 more
core   +1 more source

Development of Anticancer Agents from Plant-Derived Sesquiterpene Lactones.

open access: yesCurrent Medicinal Chemistry, 2016
Sesquiterpene lactones are of considerable interest due to their potent bioactivities, including cancer cell cytotoxicity and antineoplastic efficacy in in vivo studies.
Yulin Ren, Jianhua Yu, A. Kinghorn
semanticscholar   +1 more source

Phytochemical Investigation and Biological Evaluation of Disynaphia filifolia: A Novel Source of Tremetone in Asteraceae

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Chemical investigation of Disynaphia filifolia (Hassl.) R.M. King & H. Rob. (Asteraceae) led to the isolation of eight compounds, with tremetone being the major metabolite recovered. Tremetone has been suggested as the toxic compound in Ageratina altissima and Isocoma pluriflora, two species of the Asteraceae family. Although D.
Yasmin Rodrigues Chierici   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy