Results 81 to 90 of about 92,534 (385)
Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D.+2 more
core +2 more sources
Cytotoxic Compounds Isolated from Murraya tetramera Huang
A new compound and seven known compounds were isolated from Murraya tetramera Huang for the first time, and they were identified with NMR and MS spectral analysis. It was confirmed that the new compound was 10-methoxy-7-methyl-2H-benzo[g]chromen-2-one (3)
Chun-Xue You+9 more
doaj +1 more source
Eight new sesquiterpenes, namely, albocinnamins A−H (1−8), along with two known ones (9 and 10), have been isolated from the fungus Antrodiella albocinnamomea.
Jinlei Ning+4 more
doaj +1 more source
Catalytic Plasticity of Germacrene A Oxidase Underlies Sesquiterpene Lactone Diversification1[OPEN]
The striking catalytic plasticity of germacrene A oxidase, an evolutionary conserved enzyme in the Asteraceae, has led to the existence of diverse sesquiterpene lactones, including artemisinin.
Trinh-Don Nguyen+4 more
semanticscholar +1 more source
Sesquiterpenes in Cereals and Spices
This chapter provides an in-depth overview of the sesquiterpenes found in cereals and spices. These aliments provide an important source of nutrients for our health, and they are consumed daily. Thus, a knowledge of the constituents is vital to understand the origin of their benefits for human health as well as the possible side effects that can arise ...
Marcos Cárdenas, David+4 more
openaire +3 more sources
A Short Synthesis of Bisabolane Sesquiterpenes [PDF]
A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials.
Du, Zhen-Ting+3 more
openaire +4 more sources
In this study, we investigate the anticancer properties of phenoxyatemisinin (4) among acetal‐type artemisinin derivatives by evaluating their growth inhibitory effects on colon cancer cells and CSCs. Given their established role as potent antimalarial agents and their emerging potential in oncology, artemisinin‐based compounds offer a promising avenue
Nam Hyun Kim+3 more
wiley +1 more source
Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]
Key Points First report demonstrating in vivo elimination of multiple LIC populations from childhood ALL cases using animal models. In vivo models of leukemia are essential for drug evaluation studies.
Blair, Allison+3 more
core +1 more source
Development of Anticancer Agents from Plant-Derived Sesquiterpene Lactones.
Sesquiterpene lactones are of considerable interest due to their potent bioactivities, including cancer cell cytotoxicity and antineoplastic efficacy in in vivo studies.
Yulin Ren, Jianhua Yu, A. Kinghorn
semanticscholar +1 more source
ABSTRACT Chemical investigation of Disynaphia filifolia (Hassl.) R.M. King & H. Rob. (Asteraceae) led to the isolation of eight compounds, with tremetone being the major metabolite recovered. Tremetone has been suggested as the toxic compound in Ageratina altissima and Isocoma pluriflora, two species of the Asteraceae family. Although D.
Yasmin Rodrigues Chierici+11 more
wiley +1 more source