Plant sesquiterpene lactones. [PDF]
Philos Trans R Soc Lond B Biol SciSesquiterpene lactones (STLs) are a prominent group of plant secondary metabolites predominantly found in the Asteraceae family and have multiple ecological roles and medicinal applications. This review describes the evolutionary and ecological significance of STLs, highlighting their roles in plant defence mechanisms against herbivory and as ...
Agatha O +3 more
europepmc +5 more sources
Research progress on antitumor mechanisms and molecular targets of Inula sesquiterpene lactones [PDF]
Chinese Medicine, 2023 The pharmacological effects of natural product therapy have received sigificant attention, among which terpenoids such as sesquiterpene lactones stand out due to their biological activity and pharmacological potential as anti-tumor drugs.
Fei Cao +3 more
doaj +2 more sources
Anti-Inflammatory and Immunoregulatory Action of Sesquiterpene Lactones [PDF]
Molecules, 2022 Sesquiterpene lactones (SL), characterized by their high prevalence in the Asteraceae family, are one of the major groups of secondary metabolites found in plants.
Ana Paço +5 more
doaj +2 more sources
Sesquiterpene lactones from Vernonia [PDF]
Memorias do Instituto Oswaldo Cruz, 1991 Some informations about the sesquiterpene lactones isolated from Brazilian species of Vernonia are described, as well the results of tests developed with such compounds with respect to their anti-feedant, molluscicide, antimicrobial and analgesic ...
João Luis Callegari Lopes
doaj +4 more sources
Targeted Screening and Quantification of Characteristic Sesquiterpene Lactones in Ambrosia artemisiifolia L. at Different Growth Stages [PDF]
PlantsSesquiterpene lactones are specialized plant metabolites with promising pharmacological activities. These metabolites are characteristic marker compounds for the aerial parts of Ambrosia artemisiifolia.
Balázs Kovács +6 more
doaj +2 more sources
Method development and validation for the extraction and quantification of sesquiterpene lactones in Dolomiaea costus [PDF]
Ultrasonics SonochemistryDolomiaea costus, commonly known as Indian costus, is a medicinal plant from the Asteraceae family. The root and powder of costus have been widely used to treat various health conditions.
Mohammed Aldholmi
doaj +2 more sources
Sesquiterpene lactones as emerging biomolecules to cease cancer by targeting apoptosis [PDF]
Frontiers in PharmacologyApoptosis is a programmed cell death comprising two signaling cascades including the intrinsic and extrinsic pathways. This process has been shown to be involved in the therapy response of different cancer types, making it an effective target for ...
Chou-Yi Hsu +5 more
doaj +2 more sources
Sesquiterpene lactones. XXIII. Isolation of sesquiterpene lactones from Centaurea L. species
Acta Societatis Botanicorum Poloniae, 2014 Sesquiterpene lactones were isolated from 18 species or subspecies of the genus Centaurea L.: salonitenolide (I) was found in C. crithmifolia Vis., C. friderici Vis., C, paniculata L., C. calcitrapa L., C. pontica Prodan et E. L' Nyarady, C. eriophora L.,
Barbara Geppert +3 more
doaj +4 more sources
Conjugates of 3,5-Bis(arylidene)-4-piperidone and Sesquiterpene Lactones Have an Antitumor Effect via Resetting the Metabolic Phenotype of Cancer Cells [PDF]
MoleculesIn recent years, researchers have often encountered the significance of the aberrant metabolism of tumor cells in the pathogenesis of malignant neoplasms.
M. E. Neganova +11 more
doaj +2 more sources
Sesquiterpene Lactones Containing an α-Methylene-γ-Lactone Moiety Selectively Down-Regulate the Expression of Tumor Necrosis Factor Receptor 1 by Promoting Its Ectodomain Shedding in Human Lung Adenocarcinoma A549 Cells [PDF]
MoleculesAlantolactone is a eudesmane-type sesquiterpene lactone containing an α-methylene-γ-lactone moiety. Previous studies showed that alantolactone inhibits the nuclear factor κB (NF-κB) signaling pathway by targeting the inhibitor of NF-κB (IκB) kinase ...
Quy Van Vu +3 more
doaj +2 more sources