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Research progress on antitumor mechanisms and molecular targets of Inula sesquiterpene lactones [PDF]
Chinese Medicine, 2023 The pharmacological effects of natural product therapy have received sigificant attention, among which terpenoids such as sesquiterpene lactones stand out due to their biological activity and pharmacological potential as anti-tumor drugs.
Fei Cao +3 more
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Sesquiterpene lactones as emerging biomolecules to cease cancer by targeting apoptosis [PDF]
Frontiers in PharmacologyApoptosis is a programmed cell death comprising two signaling cascades including the intrinsic and extrinsic pathways. This process has been shown to be involved in the therapy response of different cancer types, making it an effective target for ...
Chou-Yi Hsu +5 more
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Anti-Inflammatory and Immunoregulatory Action of Sesquiterpene Lactones [PDF]
Molecules, 2022 Sesquiterpene lactones (SL), characterized by their high prevalence in the Asteraceae family, are one of the major groups of secondary metabolites found in plants.
Ana Paço +5 more
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Frontiers in Pharmacology, 2022 Cellular differentiation is pivotal in health and disease. Interfering with the process of differentiation, such as inhibiting the differentiation of adipocytes and inducing the differentiation of cancer cells, is considered a therapeutic approach ...
Sepand Tehrani Fateh +7 more
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Plant sesquiterpene lactones. [PDF]
Philos Trans R Soc Lond B Biol SciSesquiterpene lactones (STLs) are a prominent group of plant secondary metabolites predominantly found in the Asteraceae family and have multiple ecological roles and medicinal applications. This review describes the evolutionary and ecological significance of STLs, highlighting their roles in plant defence mechanisms against herbivory and as ...
Agatha O +3 more
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Biomedicines, 2021 Anthracycline antitumor antibiotics are one of the promising classes of chemotherapeutic agents for cancer treatment. The main deterrent to their use is high toxicity to a healthy environment, including cumulative cardiotoxicity.
Margarita Neganova +6 more
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Journal of Ethnopharmacology, 2022 ETHNOPHARMACOLOGICAL RELEVANCE Aucklandia lappa Decne. (ALDE) is the general name for Asteraceae plants Yunmuxiang, which has traditionally been proven to have the efficacy in relieving depression by regulating qi, alleviating cold by warming ...
Yan Chen +7 more
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Sesquiterpene Lactones as Promising Candidates for Cancer Therapy: Focus on Pancreatic Cancer. [PDF]
Molecules, 2022 Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease which confers to patients a poor prognosis at short term. PDAC is the fourth leading cause of death among cancers in the Western world.
Laurella LC +5 more
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Sesquiterpene lactones from Vernonia [PDF]
Memorias do Instituto Oswaldo Cruz, 1991 Some informations about the sesquiterpene lactones isolated from Brazilian species of Vernonia are described, as well the results of tests developed with such compounds with respect to their anti-feedant, molluscicide, antimicrobial and analgesic ...
João Luis Callegari Lopes
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Targeted Screening and Quantification of Characteristic Sesquiterpene Lactones in Ambrosia artemisiifolia L. at Different Growth Stages [PDF]
PlantsSesquiterpene lactones are specialized plant metabolites with promising pharmacological activities. These metabolites are characteristic marker compounds for the aerial parts of Ambrosia artemisiifolia.
Balázs Kovács +6 more
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