Results 91 to 100 of about 16,757 (265)
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui+17 more
wiley +1 more source
Sesquiterpene lactones from Chrysolaena platensis
Fil: Pollora, Genaro Cesar. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Tucuman. Instituto de Quimica del Noroeste. Universidad Nacional de Tucuman. Facultad de Bioquimica, Quimica y Farmacia.
Pollora, Genaro Cesar+4 more
openaire +4 more sources
EFFECTS OF LUDARTIN AND LEUKOMISIN ON THE ACUTE HYPERLIPIDEMIA MODEL INDUCED BY ETHANOL
Objective: study sesquiterpene lactones ludartin and leukomisin lipid-lowering properties on the model of acute hyperlipidemia induced by ethanol in rats.Material and methods. Rats during 7 days injected into the stomach ludartin and leukomisin in a dose
A. V. Ratkin+5 more
doaj +1 more source
Smallanthus macroscyphus: a new source of antidiabetic compounds [PDF]
The aim of the present study was to analyze the in vivo hypoglycaemic effects of both decoction of Smallanthus macroscyphus leaves and pure crystalline polymatin A isolated from its leaves.
Cabrera, Wilfredo+8 more
core +1 more source
Metabolomics revealed 24 major compounds, mainly glycosides, flavonoids, and triterpenes. Antidiabetic compounds Kaempferol‐7‐O‐rutinoside and Kaempferol‐3‐O‐rutinoside‐7‐O‐glucoside show maximum inhibiting activity for DPP4 protein (in vitro and in silico). Out of 24 compounds, 5 demonstrate no PAINS and break alerts.
Ilham Khan+7 more
wiley +1 more source
EFFECTS OF GROSSHEMIN AND GROSSMISIN ON THE ACUTE HYPERLIPIDEMIA MODEL INDUCED BY ETHANOL
Objective: study sesquiterpene lactones grosshemin and grossmisin lipid-lowering properties on the model of acute hyperlipidemia induced by ethanol in rats.Materials and methods. Rats during 7 days injected into the stomach grosshemin and grossmisin in a
A. V. Ratkin+5 more
doaj +1 more source
Antiprotozoal activity of flavonoids from Eupatorium arnottianum [PDF]
Dichloromethane and ethanol extracts of Eupatorium arnottianum were evaluated for invitroleishmanicidal activity. The dichloromethane extract produced 80% and 85% of growthinhibition on both Leishmania mexicana and Leishmania amazonensis promastigotes ...
Cazorla, Silvia Ines+7 more
core
Sesquiterpenoids in subtribe Centaureinae (Cass.) Dumort (tribe Cardueae, Asteraceae): distribution, 13C-NMR spectral data and biological properties [PDF]
Asteraceae Bercht. & J. Presl is one of the biggest and most economically important plant families. The taxonomy and phylogeny of Asteraceae is rather complex and according to the latest and most reliable taxonomic classification of Panero & Funk, based ...
Bancheva, S.+3 more
core +1 more source
Sesquiterpene lactones from Tanacetum ferulaceum
2341
González, Antonio G.+4 more
openaire +4 more sources