Results 121 to 130 of about 35,676,247 (246)

Data-set-7

, 2016
Data-set-
Craig Hartman (3329319), Jain, Chandni V., Brian A. Kilburn (3193293), Armant, D. Randall, Alan D. Bolnick (3329316), Marie van Dijk (214780), Fritz, Rani, Sascha Drewlo (105799), Chandni V. Jain (3193281), Bolnick, Alan D., Hartman, Craig, Allerdien Visser (1805944), D. Randall Armant (3193278), Leena Kadam (3329325), Vicki Mazzorana (3329331), Kadam, Leena, Hertz, Michael, Mazzorana, Vicki, Kilburn, Brian A., Rani Fritz (3329328), Dijk, Marie van, Hamid-Reza Kohan-Ghad (3329322), Drewlo, Sascha, Visser, Allerdien, Michael Hertz (3329334), Kohan-Ghad, Hamid-Reza   +25 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Translating Generalized Algebraic Data Types to System F [PDF]

Generalized algebraic data types (GADTs) extend ordinary algebraic data types by refining the types of constructors with syntactic equality constraints.
Sulzmann, Martin, Wang, Meng
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Algorithms for the identification of prevalent diabetes in the All of Us Research Program validated using polygenic scores

Scientific Reports
The All of Us Research Program (AoU) is an initiative designed to gather a comprehensive and diverse dataset from at least one million individuals across the USA.
Lukasz Szczerbinski, Ravi Mandla, Philip Schroeder, Bianca C. Porneala, Josephine H. Li, Jose C. Florez, Josep M. Mercader, Miriam S. Udler, Alisa K. Manning   +8 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Data-set-9

, 2016
Data-set-
Craig Hartman (3329319), Jain, Chandni V., Brian A. Kilburn (3193293), Armant, D. Randall, Alan D. Bolnick (3329316), Marie van Dijk (214780), Fritz, Rani, Sascha Drewlo (105799), Chandni V. Jain (3193281), Bolnick, Alan D., Hartman, Craig, Allerdien Visser (1805944), D. Randall Armant (3193278), Leena Kadam (3329325), Vicki Mazzorana (3329331), Kadam, Leena, Hertz, Michael, Mazzorana, Vicki, Kilburn, Brian A., Rani Fritz (3329328), Dijk, Marie van, Hamid-Reza Kohan-Ghad (3329322), Drewlo, Sascha, Visser, Allerdien, Michael Hertz (3329334), Kohan-Ghad, Hamid-Reza   +25 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Linked Data Mining Challenge RM Set

Rapid Miner Process files and XML test set including the predicted labels for the Linked Data Mining Challenge 2015.Rapid Miner Process files and XML test set including the predicted labels for the Linked Data Mining Challenge ...
Schaible, Johann, GESIS - Leibniz Institute for the Social Sciences
core   +1 more source