Results 71 to 80 of about 709,020 (315)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Global and local optimization algorithms for optimal signal set design
, 2001 The problem of choosing an optimal signal set for non-Gaussian detection was reduced to a smooth inequality constrained mini-max nonlinear programming problem by Gockenbach and Kearsley. Here we consider the application of several optimization algorithms,
Kearsley, A.J.
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Research on Optimization of Classification Model for Imbalanced Data Set [PDF]
Jisuanji gongcheng, 2018 In order to improve the classification efficiency of unbalanced data sets,this paper proposes a classification model.The sample sampling and classification algorithm are optimized.A new sample set is generated by cyclic sampling of the few samples of the
WEN Xueyan,CHEN Jianan,JING Weipeng,XU Kesheng
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Quasi-Newton Methods for Topology Optimization Using a Level-Set Method
, 2023 The ability to efficiently solve topology optimization problems is of great importance for many practical applications. Hence, there is a demand for efficient solution algorithms.
Kevin Sturm +4 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Solving ill-posed bilevel programs [PDF]
, 2016 This paper deals with ill-posed bilevel programs, i.e., problems admitting multiple lower-level solutions for some upper-level parameters. Many publications have been devoted to the standard optimistic case of this problem, where the difficulty is ...
Zemkoho, Alain B., Alain B. Zemkoho
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Connectedness and Contractibility of Solutions in Set Optimization Under Set Less Order Relations
Journal of MathematicsThis study establishes the topological properties of solution sets in set optimization, focusing on their connectedness and contractibility. Utilizing the arcwise convexity and lower semicontinuity characteristics derived from scalarization techniques ...
Taiyong Li, Manli Yang
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Elitism set based particle swarm optimization and its application
International Journal of Computational Intelligence Systems, 2017 Topology plays an important role for Particle Swarm Optimization (PSO) to achieve good optimization performance. It is difficult to find one topology structure for the particles to achieve better optimization performance than the others since the ...
Yanxia Sun, Zenghui Wang
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source