Results 81 to 90 of about 709,020 (315)
Data set of multi-objective optimization of diesel engine parameters
Data in Brief, 2019 This data article presents the experimental data set on the optimization of four important parameters which are type of blending fuel, blending ratio, compression ratio and injection timing for four objective functions namely higher brake thermal ...
R. Sathish Kumar, K. Sureshkumar
doaj +1 more source
Advances in Mechanical Engineering, 2022 To improve the evaluation efficiency of failure probability in RBDO models with uncertainty, many RIA-based, PMA-based methods have evolved as a powerful procedure, including the modified reliability index approach (MRIA), PMA two-level, PMA with ...
Xue An, Dongyan Shi
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Approximation hardness of dominating set problems in bounded degree graphs
, 2008 We study approximation hardness of the Minimum Dominating Set problem and its variants in undirected and directed graphs. Using a similar result obtained by Trevisan for Minimum Set Cover we prove the first explicit approximation lower bounds for various
Chlebikova, Janka +4 more
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Active Set Approach for a Bilevel Portfolio Optimization Model [PDF]
International Journal of Mathematical, Engineering and Management SciencesThis paper presents a methodology for determining the optimal portfolio that maximizes the Sharpe ratio within a bilevel framework. The upper-level of the model maximizes the Sharpe ratio of the portfolio, while the lower-level minimizes the risk for a ...
Bhuvnesh Khatana , Geetanjali Panda
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
On constrained set-valued optimization [PDF]
The set-valued optimization problem minC F(x), G(x)\(-K) 6= ; is considered, where F : Rn Rm and G : Rn Rp are set-valued functions, and C Rm and K Rp are closed convex cones.
Rocca Matteo, Ginchev Ivan
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
First order optimality condition for constrained set-valued optimization [PDF]
A constrained optimization problem with set-valued data is considered. Different kind of solutions are defined for such a problem. We recall weak minimizer, efficient minimizer and proper minimizer.
Rocca Matteo +2 more
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