Results 101 to 110 of about 1,084,937 (314)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Georg Cantor i idea jedności nauki

Zagadnienia Filozoficzne w Nauce, 2009
G. Cantor presented - in an unpublished paper (1884) - a vision of the unity of science. He argued all sciences can be reduced directly to the set theory. A source of this idea was for Cantor the unity of mathematics (on the basis of set theory).
Jerzy Dadaczyński
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Formal methods in software development: A road less travelled

South African Computer Journal, 2010
An integration of traditional verification techniques and formal specifications in software engineering is presented. Advocates of such techniques claim that mathematical formalisms allow them to produce quality, verifiably correct, or at least highly ...
John A van der Poll
doaj  

The Modal Status of Generative Principles

Metaphysics
This contribution to a symposium marking the 30th anniversary of Kit Fine’s “Essence and Modality” raises a general question for essentialist theories of modality: What sort of proposition can figure in the essence of a property? Several versions of Fine’
Gideon Rosen
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pour une formalisation du concept d’équivalence en terminologie

MediAzioni
Equivalence is a central yet often controversial concept in the field of multilingual terminology. While extensively theorized in translation studies, it remains a vague notion in terminology, situated at the intersection of conceptual and linguistic ...
Federica Vezzani
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Relative Reduction of Neighborhood-Covering Pessimistic Multigranulation Rough Set Based on Evidence Theory

, 2019
Relative reduction of multiple neighborhood-covering with multigranulation rough set has been one of the hot research topics in knowledge reduction theory.
Hongkun Wang, Jinjin Li, Xiaoying You
core   +1 more source

Set Theory

, 2011
This stimulating workshop exposed some of the most exciting recent develops in set theory, including major new results about the proper forcing axiom, stationary reflection, gaps in P(ω)/Fin, iterated forcing, the tree property, ideals and colouring ...

core   +2 more sources