Results 81 to 90 of about 10,721,723 (299)
Revista da Tulha, 2015 This paper proposes a simultaneous parallel between two different parameters of musical analysis which in our study appeared interdependent and necessary for building a sufficient theoretical framework for an understanding of the compositional aesthetic ...
Joel Miranda Bravo de Albuquerque +1 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Notre Dame Journal of Formal Logic, 2009 I argue for the use of the adjunction operator (adding a single new element to an existing set) as a basis for building a finitary set theory. It allows a simplified axiomatization for the first-order theory of hereditarily finite sets based on an induction schema and a rigorous characterization of the primitive recursive set functions.
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2008 A formulation of naïve set theory is given in Lafont’s Soft Linear Logic, a logic with polynomial time cut-elimination. We demonstrate that the provably total functions of this set theory are precisely the PTIME functions.
McKinley, Richard, Richard McKinley
core +3 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
InfinityMathematics is often perceived as culturally neutral and detached from its social and historical foundations, leading to the neglect of cultural heritage rich in mathematical ideas.
Rully Charitas Indra Prahmana +7 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source