Results 91 to 100 of about 10,721,723 (299)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Partially-elementary end extensions of countable models of set theory [PDF]

open access: yes
© The Author(s), 2025. Published by Cambridge University Press on behalf of The Association for Symbolic LogicLet KP denote Kripke–Platek Set Theory and let M be the weak set theory obtained from ZF by removing the collection scheme, restricting ...
McKenzie, Zachiri
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Generalized Ideal Gas Equations for Structureful Universe

open access: yesEntropy, 2006
We have derived generalized ideal gas equations for a structureful universe consistingof all forms of matters. We have assumed a universe that contains superclusters. Superclusters arethen made of clusters.
Khalid Khan, Shahid N. Afridi
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Optimal allocation of wind capacity considering the impact of generation uncertainty based on zonotope limited security regions

open access: yesThe Journal of Engineering, 2019
The increasing wind capacity integration brings new challenges to power system planning and operation, due to the intermittency and uncertainty of its power generations. This paper determines the optimal allocation of wind capacity with considerations of
Jianing Gao   +6 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Georg Cantor i idea jedności nauki

open access: yesZagadnienia Filozoficzne w Nauce, 2009
G. Cantor presented - in an unpublished paper (1884) - a vision of the unity of science. He argued all sciences can be reduced directly to the set theory. A source of this idea was for Cantor the unity of mathematics (on the basis of set theory).
Jerzy Dadaczyński
doaj  

On Existence in Set Theory

open access: yesNotre Dame Journal of Formal Logic, 2012
The aim of the present paper is to provide a robust classi- cation of valid sentences in set theory by means of existence and related notions and, in this way, to capture similarities and dissimilarities among the axioms of set theory. In order to achieve this, precise denitions for the notions of productive and nonproductive assertions, constructive ...
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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