Results 141 to 150 of about 1,084,937 (314)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

On the Distribution of the Prime Numbers

open access: yes
This research explores the distribution of prime numbers, which are a fundamental topic in number theory. The study originated from the author\u27s fascination with mathematics and the desire to discover something novel.
Khalil, Lolav Ahmed
core   +1 more source

On the neutrosophic soft set with rough set theory. [PDF]

open access: yesSoft comput, 2021
Das M, Mohanty D, Parida KC.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Training set edition using Rough Set Theory for Semi-supervised Classification

open access: yes, 2017
Semi-supervised Classification (SSC) is becoming an attractive research filed due to the emergence of real-world problems on which the number of unlabeled examples exceeds the labeled ones.
Nápoles, G.   +4 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Theory and problems of set theory and related topics

open access: yes, 1981
+233hlm ...
LIPSCHUTZ, SEYMOUR
core  

Classical Set Theory: Theory of Sets and Classes

open access: yes, 2020
This is a short introductory course to Set Theory, based on axioms of von Neumann--Bernays--Gödel (briefly NBG). The text can be used as a base for a lecture course in Foundations of Mathematics, and contains a reasonable minimum which a good (post-graduate) student in Mathematics should know about foundations of this science.
openaire   +2 more sources

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