Results 151 to 160 of about 1,084,937 (314)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Investigating and Modeling Colors with Set theory: A Case of Color Mixing

open access: yes, 2014
The paper introduced Colors in general and how they affect us and the environment. This work used set theory to explain the concept of Color mixing.  The idea of set can be very useful to model colors; we here consider additive and Subtractive color ...
Alhamdu, Madaki Atama   +1 more
core  

A set theory based fuzzy fs/QCA: a new tool for sensory analysis of foods

open access: yesCyTA - Journal of Food
A study was conducted to identify the closest possible contributors to human behavior during sensory evaluation of fortified yogurt. Following a numbers-only method, sensory scores (1–9) were assigned to four Attributes – Color, Taste, Texture and Flavor
JK Pallavi
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Wura Bongi Monca dance as a promising context for fostering problem-solving skills in learning set theory

open access: yesJurnal Elemen
The Wura Bongi Monca dance embodies the philosophical values of Bima culture, which can be contextualized to facilitate students' understanding of abstract mathematical concepts, such as set theory.
Khairullah   +2 more
doaj   +1 more source

Seismic vulnerability assessment of urban buildings using the rough set theory and weighted linear combination. [PDF]

open access: yesJ Mt Sci, 2022
Asadi Y   +4 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Set theory and model theory /

open access: yes, 1981
ProceedingsIncludes bibliographical ...
Prestel, Alexander(viaf)110033419   +2 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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