The effect of sevelamer carbonate and lanthanum carbonate on the pharmacokinetics of oral calcitriol. [PDF]
Lanthanum carbonate and sevelamer carbonate are non-calcium-based phosphate binders used to manage hyperphosphataemia in patients with chronic kidney disease (CKD). Patients with CKD may require intravenous or oral active vitamin D. We investigated the effects of lanthanum carbonate and sevelamer carbonate on the bioavailability of oral calcitriol.This
Pierce D +6 more
europepmc +6 more sources
A randomized, crossover design study of sevelamer carbonate powder and sevelamer hydrochloride tablets in chronic kidney disease patients on haemodialysis [PDF]
Sevelamer carbonate is an improved, buffered form of sevelamer hydrochloride developed for the treatment of hyperphosphataemia in CKD patients. Sevelamer carbonate formulated as a powder for oral suspension presents a novel, patient-friendly alternative to tablet phosphate binders.
Fan, Stanley +7 more
openaire +5 more sources
Development and validation of a gas chromatography method for the trace level determination of allylamine in sevelamer hydrochloride and sevelamer carbonate drug substances. [PDF]
A capillary gas chromatography method using a flame ionization detector has been developed for the trace analysis of allylamine (AA) in sevelamer hydrochloride (SVH) and sevelamer carbonate (SVC) drug substances. The method utilized a mega bore capillary column DB-CAM (30 m × 0.53 mm × 1.0 μm) with a bonded and cross-linked, base-deactivated ...
Kadiyala RV +7 more
europepmc +4 more sources
Phosphate binder in dialysis: a cross-sectional study of patients' adherence and pill burden [PDF]
Introduction: Phosphate (P) binders are among the most common medications prescribed to control P levels in patients with chronic kidney disease on dialysis.
Brunelle Bruna Scavello Coelho Ferezin +7 more
doaj +2 more sources
Efficacy and safety of sucroferric oxyhydroxide versus sevelamer carbonate: A systematic review and meta-analysis. [PDF]
Abstract Introduction Phosphate binders are commonly used in patients receiving kidney replacement therapy (KRT), aiming to reduce and maintain serum phosphorus. Chronic kidney disease‐mineral and bone disorder has been linked to reduced lifespan and worsened quality of life.
Georgopoulos C +5 more
europepmc +2 more sources
One case of erythroderma caused by oral administration of sevelamer carbonate
病例资料患者,男,86岁,因"腰酸不适40余年,浮肿加重伴皮肤瘙痒脱屑2周",于2020年3月15日收入南京市中医院肾内科。患者40余年前无明显诱因下出现腰酸不适,于外院诊断为"慢性肾炎综合征",间断服用中药治疗症状稍改善,未系统监测肾功能。自诉近年来血肌酐偏高(具体不详),蛋白尿波动在1+~2+。4周前因高磷血症加用碳酸司维拉姆,每次口服800 mg、3次/d降磷,服药2周后出现皮肤脱屑,瘙痒加重等症状,在我院皮肤科经诊断考虑为过敏。
Wu Zhong-fan, Kong Wei, Ni Bin
doaj +1 more source
Whitish Deposits in the Stomach and Duodenum. [PDF]
United European Gastroenterology Journal, Volume 13, Issue 10, Page 1913-1915, December 2025.
Yang KY, Zhou XJ, Xie W.
europepmc +2 more sources
P-cresyl sulfate and indoxyl sulfate are strongly associated with cardiovascular events and all-cause mortality in chronic kidney disease (CKD). This randomized controlled trial was conducted to compare the effects between sevelamer and calcium carbonate
Kullaya Takkavatakarn +10 more
doaj +1 more source
The effects of sevelamer carbonate on blood glucose and inflammatory factors in patients with diabetic kidney disease; a controlled clinical trial [PDF]
Introduction: Diabetic nephropathy (diabetic kidney disease) is a complication of diabetes that begins and progresses with several factors, including hyperglycemia, inflammation and oxidative stress.
Shadi Botshekan +5 more
doaj +1 more source
Patients with end-stage renal disease (ESRD) present alterations in mineral and bone metabolism. Hyperphosphatemia in ESRD is considered an independent risk factor for cardiovascular disease (CVD), increasing morbidity, and mortality.
Elodia Nataly Díaz-De la Cruz +8 more
doaj +1 more source

