Effect of Sevelamer on Calciprotein Particles in Hemodialysis Patients: The Sevelamer Versus Calcium to Reduce Fetuin-A-Containing Calciprotein Particles in Dialysis (SCaRF) Randomized Controlled Trial [PDF]
Kidney International Reports, 2020 Introduction: Calciprotein particles (CPPs) are potentially modifiable mediators of phosphate toxicity in patients with kidney disease. We compared the effects of calcium carbonate (CC) and the non–calcium-based phosphate binder sevelamer on CPP levels ...
Edward R. Smith +4 more
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Sevelamer-Induced Gastrointestinal Injury Presenting as Gastroenteritis [PDF]
Case Reports in Gastroenterology, 2018 End-stage renal disease (ESRD) is a common disease encountered in clinical practice and is associated with increasing metabolic derangements through disease progression.
Jared Magee +2 more
doaj +3 more sources
The Effects of Sevelamer Hydrochloride and Calcium Carbonate on Kidney Calcification in Uremic Rats [PDF]
Journal of the American Society of Nephrology, 2002 The control of serum phosphorus (P) and calcium-phosphate (Ca x P) product is critical to the prevention of ectopic calcification in chronic renal failure (CRF). Whereas calcium (Ca) salts, the most commonly used phosphate binders, markedly increase serum Ca and positive Ca balance, the new calcium- and aluminum-free phosphate binder, sevelamer ...
M. Cozzolino +6 more
openaire +5 more sources
A Pan-Inhibitor of Phosphate Transporters AP306 in Hemodialysis Patients [PDF]
Kidney International ReportsIntroduction: Hyperphosphatemia in patients undergoing dialysis is not well-controlled. AP306 is a pan-inhibitor of phosphate transporters, designed to block the active uptake of phosphate through the gastrointestinal tract.
Li Wang +14 more
doaj +3 more sources
Sevelamer Carbonate Reduces Inflammation and Endotoxemia in an Animal Model of Uremia
Blood Purification, 2010 <i>Background:</i> Renal failure is associated with activation of inflammatory response, but the mechanisms behind this observation and potential anti-inflammatory strategies are yet to be defined. Endotoxin (ET) translocation from the intestinal lumen can potentially trigger systemic inflammatory response, and ET binding represents a ...
Aline B, Hauser +5 more
openaire +3 more sources
Therapeutics and Clinical Risk Management, 2015 Lin Meng,1,2 Bin Fu1 1Department of Nephrology, Second Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China; 2Tianjin University of Traditional Chinese Medicine, Tianjin, People’s ...
Meng L, Fu B
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Phosphate binder in dialysis: a cross-sectional study of patients' adherence and pill burden [PDF]
Brazilian Journal of NephrologyIntroduction: Phosphate (P) binders are among the most common medications prescribed to control P levels in patients with chronic kidney disease on dialysis.
Brunelle Bruna Scavello Coelho Ferezin +7 more
doaj +2 more sources
Randomized Clinical Trial of Sevelamer Carbonate on Serum Klotho and Fibroblast Growth Factor 23 in CKD. [PDF]
Clin J Am Soc Nephrol, 2017 International audienceBackground and objectives: Epidemiologic studies suggest that higher serum phosphaturic hormone fibroblast growth factor 23 levels are associated with increase morbidity and mortality.
Liabeuf S +13 more
europepmc +2 more sources
Cogent Medicine, 2016 Introduction: Lanthanum carbonate (LC) and sevelamer hydrochloride (SH) are non-calcium-based phosphate binders (NCPB), used to manage hyperphosphatemia in patients with chronic kidney disease.
Asrar Khan +6 more
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One case of erythroderma caused by oral administration of sevelamer carbonate
Linchuang shenzangbing zazhi, 2021 病例资料患者,男,86岁,因"腰酸不适40余年,浮肿加重伴皮肤瘙痒脱屑2周",于2020年3月15日收入南京市中医院肾内科。患者40余年前无明显诱因下出现腰酸不适,于外院诊断为"慢性肾炎综合征",间断服用中药治疗症状稍改善,未系统监测肾功能。自诉近年来血肌酐偏高（具体不详）,蛋白尿波动在1+～2+。4周前因高磷血症加用碳酸司维拉姆,每次口服800 mg、3次/d降磷,服药2周后出现皮肤脱屑,瘙痒加重等症状,在我院皮肤科经诊断考虑为过敏。
Wu Zhong-fan, Kong Wei, Ni Bin
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