Results 21 to 30 of about 2,895 (208)

Repurposing of sevelamer as a novel antidote against aluminum phosphide poisoning: An in vivo evaluation

Heliyon, 2023
Aluminum phosphide (AlP) is widely used for protecting grains from pests. AlP releases toxic phosphine gas (PH3) while exposed to humidity. Poisoning with these tablets is dangerous and can cause death or serious injuries. Up to now, no definite antidote
Reza Heidari, Hamid Reza Mohammadi, Fazel Goudarzi, Fatemeh Farjadian   +3 more
doaj   +1 more source

Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding

Frontiers in Medicine, 2023
Chronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD.
Margareta Fistrek Prlic, Mislav Jelakovic, Marko Brinar, Marko Brinar, Dora Grgic, Ivan Romic, Zlatko Marusic, Ema Ivandic, Bojan Jelakovic, Bojan Jelakovic, Ivana Vukovic Brinar, Ivana Vukovic Brinar, Zeljko Krznaric, Zeljko Krznaric   +13 more
doaj   +1 more source

Evaluation of the In Vitro Efficacy of Sevelamer Hydrochloride and Sevelamer Carbonate [PDF]

Journal of Pharmaceutical Sciences, 2016
The objective of this project is to develop an in vitro approach that can be used to determine the phosphate binding capacity of sevelamer hydrochloride and carbonate for both drug products and active pharmaceutical ingredients (APIs). A simple and efficient inductively coupled plasma spectrometer method for analysis of phosphate at physiologically ...
Yongsheng, Yang, Adil, Mohammad, Robert T, Berendt, Alan, Carlin, Mansoor A, Khan, Patrick J, Faustino   +5 more
openaire   +2 more sources

Lower gastrointestinal bleeding in a patient receiving sevelamer: Case report

SAGE Open Medical Case Reports, 2021
Phosphate binders such as sevelamer are widely used in patients with chronic kidney disease to lower serum phosphate levels. We present a case of a 67-year-old woman with lower gastrointestinal bleeding after 9 days of using sevelamer carbonate (Renvela ®
Tessa S Schoot, Tessa EH Römkens, Ellen K Hoogeveen   +2 more
doaj   +1 more source

Evaluation of a Phosphate Management Protocol to Achieve Optimum Serum Phosphate Levels in Hemodialysis Patients [PDF]

, 2008
Original article can be found at: http://www.sciencedirect.com/science/journal/10512276 Copyright National Kidney Foundation, Inc. DOI: 10.1053/j.jrn.2008.05.003To evaluate the effectiveness of a protocol designed to optimize serum phosphate levels in ...
Cheung, C.F., Cunningham, J., Fan, S., Glass, G., Madden, A.M., Yokum, D.   +5 more
core   +1 more source

Response of different PTH assays to therapy with sevelamer or CaCO and active vitamin D sterols [PDF]

, 2009
Amino-terminally truncated parathyroid hormone (PTH) fragments are detected to differing degrees by first- and second-generation immunometric PTH assays (PTH-IMAs), and acute changes in serum calcium affect the proportion of these fragments in ...
Katherine Wesseling-Perry, G. Chris Harkins, He-Jing Wang, Shobha Sahney, Barbara Gales, Robert M. Elashoff, Harald Jüppner, Isidro B. Salusky, LD Quarles, H Jüppner, JH Brossard, R Lepage, P Boudou, A Fujimori, E Slatopolsky, L Nguyen-Yamamoto, P D’Amour, MR John, MC Monier-Faugere, IB Salusky, SC Waller, G Coen, KJ Martin, MC Monier-Faugere, IB Salusky, IB Salusky, AM Parfitt, RA Upton, GM Chertow, GA Block, GA Block, GA Block, DS Milliner, BY Liu, P D’Amour   +34 more
core   +1 more source

The Effect of Sevelamer on Serum Levels of Gut-Derived Uremic Toxins: Results from In Vitro Experiments and A Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial

Toxins, 2019
High serum levels of gut-derived uremic toxins, especially p-cresyl sulfate (pCS), indoxyl sulfate (IS) and indole acetic acid (IAA), have been linked to adverse outcomes in patients with chronic kidney disease (CKD).
Youssef Bennis, Yan Cluet, Dimitri Titeca-Beauport, Najeh El Esper, Pablo Ureña, Sandra Bodeau, Christian Combe, Bertrand Dussol, Denis Fouque, Gabriel Choukroun, Sophie Liabeuf   +10 more
doaj   +1 more source

Preclinical Pharmacokinetics, Pharmacodynamics and Safety of Sucroferric Oxyhydroxide. [PDF]

, 2014
Sucroferric oxyhydroxide (VELPHORO(®)) is a polynuclear iron-based phosphate binder recently approved for the treatment of hyperphosphataemia in patients with chronic kidney disease (CKD). As a number of the available phosphate binders do not provide the
Cozzolino, M., Funk, F., Phan, O., Rakov, V., Teitelbaum, I.   +4 more
core   +1 more source

Sevelamer-associated ischemic colitis with perforation

Gastroenterology Insights, 2015
We present a case of an 83-year-old woman with end-stage renal disease and hyperphosphatemia treated with sevelamer carbonate, who underwent subtotal colectomy for diffuse bowel necrosis and two perforations in the transverse colon.
Rachel Hudacko, Peter Kaye
doaj   +1 more source

Meta-analysis of the efficacy and safety of sevelamer as hyperphosphatemia therapy for hemodialysis patients

Renal Failure, 2023
This study was designed to examine the relative safety and efficacy of sevelamer in the treatment of chronic kidney disease (CKD) patients in comparison to placebo, calcium carbonate (CC), or lanthanum carbonate (LC). The PubMed, Embase, Cochrane Library,
Qian Zeng, Yuanlong Zhong, Xiqiu Yu
doaj   +1 more source