Results 111 to 120 of about 362,184 (267)

Use of whole-genome sequencing to investigate a cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in emergency department personnel

open access: green, 2021
E. Ricky Chan   +9 more
openalex   +2 more sources

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

Peptide nucleic acid biosensors: Structure–interface interactions, electrochemical signal strategies, and diagnostic applications

open access: yesVIEW, EarlyView.
This review discusses the structural and functional properties of peptide nucleic acid (PNA)‐based biosensors, emphasizing their sensitivity, enzymatic resistance, and diagnostic potential. It presents a comparative analysis of detection limits across sensor designs, focusing on probe immobilization, electrode composition, and signal amplification. The
Younghwan Kim, Swomitra Kumar Mohanty
wiley   +1 more source

Severe acute respiratory syndrome coronavirus 2: Oncology-related perceptions

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU, 2021
Atin Singhai, Parul Jain, Ranjan Solanki
doaj   +1 more source

mRNA induced expression of human angiotensin-converting enzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2 [PDF]

open access: green, 2020
Mariah Hassert   +8 more
openalex   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Crystallographic fragment screening against SARS‐CoV‐2 nonstructural protein 1 using the F2X‐Entry Screen and a newly developed fragment library

open access: yesActa Crystallographica Section D, EarlyView.
Two crystallographic fragment screening campaigns against SARS‐CoV‐2 nonstructural protein 1 resulted in the identification of 21 new hits.Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) continues to threaten global health. This underpins the need for novel therapeutics against this virus.
Frank Lennartz   +9 more
wiley   +1 more source

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