Results 161 to 170 of about 569,433 (400)

Emerging viral respiratory tract infections—environmental risk factors and transmission [PDF]

, 2014
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Charrel, Remi N., Gautret, Philippe, Gray, Gregory C., Memish, Ziad A., Odezulu, Nnanyelugo G., Zumla, Alimuddin   +6 more
core   +1 more source

Isolation and characterization of severe acute respiratory syndrome coronavirus 2 in Turkey

PLOS ONE, 2020
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and associated with severe respiratory illness emerged in Wuhan, China, in late 2019. The virus has been able to spread promptly across all continents in the world. The current pandemic has posed a great threat to public health concern and safety.
Shaikh Terkis Islam Pavel, Hazel Yetiskin, Gunsu Aydin, Can Holyavkin, Muhammet Ali Uygut, Zehra Bestepe Dursun, İlhami Celik, Ceren Cevik, Aykut Ozdarendeli   +8 more
openaire   +5 more sources

Chemically Synthesized LRAD3‐D1 Interacts with N‐Terminal Domain of SARS‐CoV‐2 Spike Protein

ChemBioChem, EarlyView.
Chemical synthesis, calcium‐templated in‐vitro folding and competitive ELISA assay reveal that only domain 1 of the LRAD3 ectodomain interacts with the severe acute respiratory syndrome‐related corona virus 2 (SARS‐CoV‐2) spike NTD, while domains 2 and 3 do not, providing valuable insight into ACE2‐independent viral entry pathways that may contribute ...
Mrinmoy Jana, Rathina Delipan, Arighna Sarkar, Sreejith Raran‐Kurussi, Rajesh P. Ringe, Kalyaneswar Mandal   +5 more
wiley   +1 more source

Airborne transmission of severe acute respiratory syndrome coronavirus‐2 to healthcare workers: a narrative review

Anaesthesia, 2020
Healthcare workers are at risk of infection during the severe acute respiratory syndrome coronavirus‐2 pandemic. International guidance suggests direct droplet transmission is likely and airborne transmission occurs only with aerosol‐generating ...
N. Wilson, A. Norton, F. Young, D. Collins   +3 more
semanticscholar   +1 more source

Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic

Archives of Pathology & Laboratory Medicine, 2020
Context.—The novel coronavirus disease 2019 (COVID-19) pandemic is significantly changing methodologic approaches in all branches of the health system. From a forensic point of view, this event is partly changing the manner in which forensic pathologists and all those who work in autopsy services operate, but above all, it is changing the patterns ...
Aquila, Isabella, Sacco, Matteo Antonio, Abenavoli, Ludovico, Malara, Natalia, Arena, Vincenzo, Grassi, Simone, Ausania, Francesco, Boccuto, Luigi, Ricci, Cristoforo, Gratteri, Santo, Oliva, Antonio, Ricci, Pietrantonio   +11 more
openaire   +7 more sources

Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry

ChemMedChem, EarlyView.
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali, Samet Poyraz, Samet Belveren, Senanur Taş, Mehmet Ali Tamer, Naciye Yaktubay Döndaş, H. Ali Döndaş, Jose Miguel Sansano   +7 more
wiley   +1 more source

Safety and Pharmacokinetics of Long‐Acting Monoclonal Antibodies Tixagevimab and Cilgavimab (AZD7442) in a China Phase 2 Study and Evaluation of Asian Race Effect

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Safety, pharmacokinetics, and impact of race of pharmacokinetics on monoclonal antibodies tixagevimab and cilgavimab (AZD7442) were assessed in Chinese adult participants in a Phase 2, randomized, double‐blind, placebo‐controlled trial. In total, 272 participants were randomized 3:1 to a single intravenous dose of 600 mg AZD7442 or placebo and
Jing Zhang, Huixia Zhang, Yajuan Zhang, Shuyuan Liu, Xiaoyun Ge, Haiyue Zhang, Yunfei Li, Cecil Chi‐Keung Chen, Oleg Stepanov, Weifeng Tang, Wenhong Zhang   +10 more
wiley   +1 more source

Covid-19 immune mechanisms: A systematic review

Indian Journal of Allergy Asthma and Immunology, 2020
There is a new public health crises threatening globally with the emergence and spread of 2019 novel coronavirus or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Shalini Gandhi, Sandeep Kumar Sharma, Purva Shoor, Jitender Sorout, Abhay Raina, Rohit Raina, Urvashi Miglani, Uma Kant Chaudhari, Shivi Srivastava   +8 more
doaj   +1 more source

Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong.

, 2003
BACKGROUND: Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS).
Abu-Raddad, Laith J, Anderson, Roy M, Chan, King-Pan, Chau, Patsy, Donnelly, Christl A, Ferguson, Neil M, Fraser, Christophe, Ghani, Azra C, Hedley, Anthony J, Ho, Lai-Ming, Kong, James HB, Lam, Tai-Hing, Lau, Edith MC, Leung, Gabriel M, Liu, Shao-Haei, Riley, Steven, Thach, Thuan-Quoc, Tsang, Thomas, Tse, Lai-Yin   +18 more
core   +1 more source

Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection

JAMA Network Open, 2020
Key Points Question In a large county health care system with access to inpatient and outpatient testing, is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection associated with pregnancy outcomes, maternal illness severity, placental ...
E. Adhikari, Wilmer Moreno, Amanda C. Zofkie, Lorre MacDonald, D. McIntire, R. Collins, C. Spong   +6 more
semanticscholar   +1 more source