Results 131 to 140 of about 3,446,938 (405)

Cognitive Outcome in Young Adults after Resolution of Epilepsy in Childhood

Annals of Neurology, EarlyView.
Self‐limited epilepsies of childhood are common and were considered benign. We aim to determine whether cognitive function in young adults who experienced epilepsy as children and are subsequently seizure‐free and unmedicated differ from the general population. We report on a cross‐sectional population‐based study including 2,124,871 men and women aged
Jacob Megreli, Leo Arkush, Estela Derazne, Arnon Afek, Gilad Twig, Bruria Ben‐Zeev, Jaana Ahonniska Assa, Gali Heimer   +7 more
wiley   +1 more source

Classification of asthma severity: Severe/not severe asthma or mild/moderate/severe asthma?

Tuberk Toraks, 2022
İnsu Yılmaz, Gülden Paçacı Çetin, Bahar Arslan   +2 more
openaire   +4 more sources

Efficacy of azithromycin in severe asthma from the AMAZES randomised trial

ERJ Open Research, 2019
Background Low-dose azithromycin is an effective therapy for persistent asthma; however, its benefit in severe asthma is not defined. Methods Participants with severe asthma were identified from the AMAZES randomised, placebo-controlled trial of long ...
Peter G. Gibson, Ian A. Yang, John W. Upham, Paul N. Reynolds, Sandra Hodge, Alan L. James, Christine Jenkins, Matthew J. Peters, Guy B. Marks, Melissa Baraket, Heather Powell, Jodie L. Simpson   +11 more
doaj   +1 more source

Biologic Therapies for Severe Asthma.

New England Journal of Medicine, 2022
G. Brusselle, G. Koppelman
semanticscholar   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

The Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar   +15 more
wiley   +1 more source

Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC) [PDF]

, 2010
Objectives: To investigate the effect of ambient particulate matter on variation in childhood prevalence of asthma, rhinoconjunctivitis and eczema.
Anabwani, G., Anderson, H. R., Asher, M. I., Aït-Khaled, N., Beasley, R., Björkstén, B., Brunekreef, B., Burr, M. L., Clayton, T. O., Crane, J., Ellwood, P., Kapetanakis, V., Keil, U., Lai, C. K. W., Mallol, J., Martinez, F. C., Mitchell, E. A., Montefort, S., Mutius, Erika von, Pandey, K.D., Pearce, N., Robertson, C. F., Ruggles, R., Shah, J. R., Stewart, A. W., Strachan, D. P., Weiland, S. K., Williams, H. C.   +27 more
core   +1 more source

Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma.

American Journal of Respiratory and Critical Care Medicine, 2019
Rationale: Corticosteroids (CSs) are the most effective asthma therapy, but responses are heterogeneous and systemic CSs lead to long-term side effects.
Wei Wu, Seo-Jin Bang, E. Bleecker, M. Castro, Loren C Denlinger, S. Erzurum, J. Fahy, A. Fitzpatrick, B. Gaston, A. Hastie, E. Israel, N. Jarjour, B. Levy, D. Mauger, D. Meyers, W. Moore, M. Peters, B. Phillips, W. Phipatanakul, R. Sorkness, S. Wenzel   +20 more
semanticscholar   +1 more source

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The phase 3 MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E. Wechsler, Jared Silver, Gerhard Wolff, Robert G. Price, Rejina Verghis, Peter F. Weller, Peter A. Merkel, Paneez Khoury, on behalf of the EGPA Mepolizumab Open‐Label Extension study group, Arnaud Bourdin, Pascal Chanez, Anoop Chauhan, Vincent Cottin, Gerald Gleich, Berhnard Hellmich, Tomonori Ishii, David Jayne, Jean‐Emmanuel Kahn, Peter Kern, Nader Khalidi, Ina Koetter, Carol Langford, Amy Markezich, Paul Monach, Shamsa Naveed, Peter Oelzner, Kenneth Pinna, Xavier Puechal, Emory H. Robinette, Florence Roufosse, Reinhard Voll, Andrew Schafer, Kaharu Sumino, Masami Taniguchi, Phillip Lieberman   +34 more
wiley   +1 more source

Personalized medicine with biologics for severe type 2 asthma : current status and future prospects [PDF]

, 2017
Asthma affects more than 300 million people worldwide and poses a large socioeconomic burden, particularly in the 5% to 10% of severe asthmatics. So far, each entry of new biologics in clinical trials has led to high expectations for treating all severe ...
Blanchetot, Christophe, Brusselle, Guy, de Haard, Hans, Godar, Marie, Lambrecht, Bart   +4 more
core   +3 more sources

Asthma Is More Severe in Older Adults.

PLoS ONE, 2015
BackgroundSevere asthma occurs more often in older adult patients. We hypothesized that the greater risk for severe asthma in older individuals is due to aging, and is independent of asthma duration.MethodsThis is a cross-sectional study of prospectively
Joe G Zein, Raed A Dweik, Suzy A Comhair, Eugene R Bleecker, Wendy C Moore, Stephen P Peters, William W Busse, Nizar N Jarjour, William J Calhoun, Mario Castro, K Fan Chung, Anne Fitzpatrick, Elliot Israel, W Gerald Teague, Sally E Wenzel, Thomas E Love, Benjamin M Gaston, Serpil C Erzurum, Severe Asthma Research Program   +18 more
doaj   +1 more source