Results 141 to 150 of about 4,122,734 (351)

Impedance‐Controlled Multipoint Radiofrequency Ablation for Chronic Rhinitis: A Randomized Controlled Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The purpose of this randomized controlled trial (RCT) was to demonstrate that posterior nasal nerve ablation treatment with the NEUROMARK System is superior to a sham control procedure in patients with chronic rhinitis. Methods In this prospective, multicenter, single‐blinded, superiority RCT, 132 participants were randomized 2:1 to
Masayoshi Takashima, Randall A. Ow, Richard D. Thrasher, Ellen M. O'Malley, William R. Blythe, Omar G. Ahmed   +5 more
wiley   +1 more source

Utility of impulse oscillometry in patients with moderate to severe persistent asthma [PDF]

, 2016
Outcomes measured with impulse oscillometry are more closely related to asthma control than spirometry in moderate to severe ...
Juniper, Juniper, Lipworth, Manoharan, Manoharan, Martin, McFadden, Meltzer, Shi   +8 more
core   +2 more sources

Appropriate Medical Therapy Primarily Modifies Type 2 and Severity Biomarkers in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park, Brooke N. Gleason, Eli Stein, Saied Ghadersohi, Atsushi Kato, Stephanie Shintani‐Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Bruce K. Tan   +9 more
wiley   +1 more source

Burden of asthma exacerbations and health care utilization in pediatric patients with asthma in the US and England

Immunity, Inflammation and Disease, 2020
Background Data on asthma burden in pediatric patients are limited; this real‐world study investigated exacerbation frequency and health care resource utilization (HCRU) in pediatric asthma patients from the US and England.
Mugdha Gokhale, Takako Hattori, Lee Evitt, Warren Lenney, Beth Nordstrom, Jenna Collins, Anna Schultze, Melissa K. Van Dyke   +7 more
doaj   +1 more source

New targets for resolution of airway remodeling in obstructive lung diseases. [PDF]

, 2018
Airway remodeling (AR) is a progressive pathological feature of the obstructive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).
Deshpande, Deepak A., Nayak, Ajay P., Penn, Raymond B   +2 more
core   +2 more sources

Interleukin-5 in the Pathophysiology of Severe Asthma

Frontiers in Physiology, 2019
Interleukin-5 (IL-5) exerts a central pathogenic role in differentiation, recruitment, survival, and degranulation of eosinophils. Indeed, during the last years, significant advances have been made in our understanding of the cellular and molecular ...
C. Pelaia, G. Paoletti, F. Puggioni, F. Racca, G. Pelaia, G. Canonica, E. Heffler   +6 more
semanticscholar   +1 more source

Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman, Spencer Short, Emma Tam, Benjamin F. Bitner, Abdulghafoor Alani, Marc Rosen, Mindy Rabinowitz, Damaris Pena Evertz, Elina Toskala, Gurston G. Nyquist   +9 more
wiley   +1 more source

Combination formoterol and budesonide as maintenance and reliever therapy versus inhaled steroid maintenance for chronic asthma in adults and children (Review) [PDF]

, 2009
Background Traditionally inhaled treatment for asthma has been considered as preventer and reliever therapy. The combination of formoterol and budesonide in a single inhaler introduces the possibility of using a single inhaler for both prevention and ...
Adams, Balanzat, Bateman, Berggren, Bisgaard, Bisgaard, Bleecker, Bousquet, Bruce, Buhl, Buhl, Cates, Cates Christopher, D'Urzo, Greenstone, Haahtela, Haahtela, Higgins, Higgins, Ind, Jenkins, Johansson, Jonkers, Kuna, Kuna, Lasserson, Loukides, Lundborg, Ni Chroinin, O'Byrne, O'Byrne, O'Byrne, O'Byrne, O'Byrne, O'Byrne, Palmqvist, Price, Price, Rabe, Rabe, Rabe, Richter, Scicchitano, Sears, Sovani, Tattersfield, Tattersfield, Vogelmeier, Vogelmeier, Vogelmeier, Walters   +50 more
core   +1 more source

Effect of Budesonide Nasal Irrigation in Patients With Chronic Rhinosinusitis With Nasal Polyps Without Prior Sinus Surgery: A Randomized, Double‐Blind, Placebo‐Controlled Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The indication for nasal irrigation with corticosteroids after sinus surgery in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is well established, as surgery facilitates distribution throughout the sinonasal cavity.
Juliana Sant'Ana, Isabela Pontes, Caio Floriano, Renato Rios, Marlos Cortez, Marcel Miyake   +5 more
wiley   +1 more source

Severe Asthma [PDF]

Annals of the American Thoracic Society, 2014
Carey C, Thomson, Carolyn H, Welsh, Margaret A, Carno, Sally E, Wenzel, Fan, Chung, Jan L, Brozek, Kevin C, Wilson   +6 more
openaire   +3 more sources