Exploration, EarlyView.The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang +15 more
wiley +1 more source
CORRECTION OF EQUINE SEVERE COMBINED IMMUNODEFICIENCY BY BONE MARROW TRANSPLANTATION
, 1986 Charles M. Bue +6 more
openalex +1 more source
Bone marrow transplantation (BMT) in Europe for primary immunodeficiencies other than severe combined immunodeficiency: a report from the European Group for BMT and the European Group for Immunodeficiency [PDF]
, 1994 Alain Fischer +9 more
openalex +1 more source
Synthetic Biology‐Based Engineering Cells for Drug Delivery
Exploration, EarlyView.Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi +4 more
wiley +1 more source
Paradoxical Enhancement of Tumor Growth in Mice with Severe Combined Immunodeficiency which Produce a Human Immunoglobulin G Reactive against Tumor Cells [PDF]
, 1994 Toshiharu Furukawa +3 more
openalex +1 more source
The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated‐B Cells
Exploration, EarlyView.Bcas2 recruits DHX15 and SRSF7 to form a protein complex for the splicing of CSR‐related mRNA at the 5' ss and 3' ss, generating two mature mRNA isoforms, which are ultimately translated into CSR‐related proteins. These CSR‐related proteins bind to DNA associated with antibodies, affecting the DSB repair of the relevant DNA after AID induction, thereby
Yu Chen +29 more
wiley +1 more source
A novel 268 kb deletion combined with a splicing variant in IL7R causes of severe combined immunodeficiency in a Chinese family: a case report. [PDF]
BMC Med Genomics, 2023 Yan L +7 more
europepmc +1 more source
1 DEVELOPMENT OF LYMPHOMAS IN HUMAN ORIGIN IN MICE WITH SEVERE COMBINED IMMUNODEFICIENCY (SCID): ROLE OF EPSTEIN-BARR VIRUS (EBV) AND INTERLEUKIN-6 (IL-6) [PDF]
, 1991 David Nadal +3 more
openalex +1 more source
Delivery of Natural Small Molecules Through Nanocarriers for Cancer Treatment
Food Frontiers, EarlyView.Natural small molecules through nanocarriers for cancer treatment ABSTRACT Cancer is a formidable adversary, accounting for the second highest number of fatalities worldwide. A multitude of studies have indicated that naturally sourced small‐molecule compounds, owing to their low toxicity and multi‐target capabilities, significantly aid in the fight ...
Fangting Ye +7 more
wiley +1 more source
Corrigendum: A Novel Homozygous JAK3 Mutation Leading to T-B+NK- SCID in Two Brazilian Patients
Frontiers in Pediatrics, 2018 Lucila A. Barreiros +6 more
doaj +1 more source