Results 171 to 180 of about 100,891 (207)

Gastroesophageal reflux and severe combined immunodeficiency

Journal of Allergy and Clinical Immunology, 1997
Gastrointestinal and respiratory symptoms and failure to thrive not associated with infections or medications were noted in patients with severe combined immunodeficiency.The aim of our study was to determine the frequency of gastroesophageal reflux in patients with severe combined immunodeficiency.We studied the case histories of 73 pediatric patients
A, Boeck, R H, Buckley, R I, Schiff
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Progress in the Classification of Severe Combined Immunodeficiency

Pediatrics, 1989
Severe combined immunodeficiency is a heterogeneous group of disorders occurring mostly in infants with severe and potentially fatal defects of both cell-mediated and humoral immunity. Failure to thrive, intractable diarrhea, and pneumonia are their most prominent clinical features.
J R, Regueiro, P, Perez-Aciego, J, Manzanares, G, Garcia-Hernandez, A, Arnaiz-Villena   +4 more
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Gene therapy for severe combined immunodeficiencies

Expert Opinion on Biological Therapy, 2005
Severe combined immune deficiencies (SCIDs) are a group of monogenic diseases resulting in profound disturbances of lymphocyte development and function. Affected individuals are prone to life-threatening infections and without treatment do not survive beyond the first year of life.
H Bobby, Gaspar, Adrian J, Thrasher
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Severe combined immunodeficiencies and related disorders

Nature Reviews Disease Primers, 2015
Severe combined immunodeficiencies (SCIDs) comprise a group of rare, monogenic diseases that are characterized by an early onset and a profound block in the development of T lymphocytes. Given that adaptive immunity is abrogated, patients with SCID are prone to recurrent infections caused by both non-opportunistic and opportunistic pathogens, leading ...
Alain, Fischer, Luigi D, Notarangelo, Bénédicte, Neven, Marina, Cavazzana, Jennifer M, Puck   +4 more
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PRENATAL DIAGNOSIS OF SEVERE COMBINED IMMUNODEFICIENCY

The Lancet, 1982
D C, Linch, C H, Rodeck, H A, Simmonds, R J, Levinsky   +3 more
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Domestic animal models of severe combined immunodeficiency: canine X-linked severe combined immunodeficiency and severe combined immunodeficiency in horses.

Immunodeficiency reviews, 1993
This review describes the clinical, immunologic and pathologic features of two naturally-occurring models of severe combined immunodeficiency (SCID) in domestic animals that represent different forms of human SCID. Canine X-linked SCID (XSCID) has an X-linked recessive mode of inheritance and, as such, represents a model for the most common form of ...
P J, Felsburg, R L, Somberg, L E, Perryman   +2 more
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Severe combined immunodeficiencies.

Immunodeficiency reviews, 1992
Severe combined immunodeficiencies (SCID) represent an heterogeneous group of diseases characterized by a profound defect in either T cell differentiation or function. The molecular nature of the defect has so far been defined for a small number of SCID, i.e. purin metabolism enzyme deficiencies.
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Treatment of severe combined immunodeficiency by transplantation

Blut, 1981
This review is meant to show that all approaches other than the use of genotypically or phenotypically identical family donors for bone marrow transplantation aimed at the treatment of SCID leave a lot of unsolved questions open. The results are inconsistant but successful cases have been reported with the various methods.
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Severe Combined Immunodeficiency Disease

2011
Militsakh, O., Day, T., Hornig, J., Lentsch, E., Skoner, J., Gillespie, M., Sharma, A., Neville, B., Rumboldt, Z., James, R., Goddard, J., Shikata, K., Doi, Y., Rosen, E. M., Goldberg, I. D., Fan, S., Kong, L., Lu, J. J., Chlenski, A., Cohn, S. L., Hlubek, F., Qian, C.-N., Teh, B. T., Batistatou, A., Charalbopoulos, K., Christensen, C., Reddel, R., Ploeg, I. M. C., Kroon, B. B. R., Nieweg, O. E., Rijk, M. C., Winqvist, O., Thorn, M., Zwick, C., Pfreundschuh, M., Knudsen, B. S., Lucas, J., Nelson, P., Kashikar, N., Datta, P. K., Hottinger, A. F., Hormigo, A., Knobler, E., Knobler, R., McCarty, J. H., Bardia, A., Loprinzi, C., Buettner, R., Jove, R., Garcia, R., Frank, D. A., Nakatsura, T., Witt, O., Yoshida, K., Chou, P.-L., Tsay, G. J., Takeuchi, T., Furihata, M., Robertson, F. M., Werbowetski-Ogilvie, T. E., Maestro, R. F., Sadr, M. S., Dennler, S., Dijke, P., Gadgeel, S., Tierauch, K.-H., Yip, K. W., Liu, F.-F., Cano, A., Neto, M. A., Rünger, T. M., Frühwald, Michael C., Trakhtenbrot, L., Mi, J., Larner, J. M., Hamlin, J. L., Radin, N. S., Lo, T. L., Guy, G. R., Yeudall, W. A., Parsons, S. J., Fan, F., Platanias, L. C., Mcgahren-Murray, M., Keyomarsi, K., Kos, J., Seigel, G. M., Alison, M. R., Hiyama, E., Renehan, A. G., Potten, C. S., Tang, D. G., Foster, P., Lin, K., Bergelt, C., Ronai, Z., Cukierman, E., Aumercier, M., Hodson, M., Lolis, E., Mehta, A., Chung, F.-L., Glatt, H., Oberthür, A., Warnat, P., Aranda, S., Culig, Z., Chung, B. H., Shin, Y.-B., Kim, M., Grevenstein, W. M. U., van Eijck, C. H. J., Baker, S. G., Kramer, B. S., Mahotka, C., Carbone, M., Yang, H., Mueller, S. C., Coopman, P. J., Brujin, D., Kessel, A. D., George, J. M.   +121 more
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Review of Treatment for Adenosine Deaminase Deficiency (ADA) Severe Combined Immunodeficiency (SCID)

Therapeutics and Clinical Risk Management, 2022
Elizabeth Secord, Nicholas L Hartog
exaly