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A high-quality severe combined immunodeficiency (SCID) rat bioresource
A high-quality severe combined immunodeficiency (SCID) rat bioresourceopenaire
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Severe Combined Immunodeficiency (SCID)—the Irish Experience
Journal of Clinical Immunology, 2021H. Burns +7 more
semanticscholar +3 more sources
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease.
Science, 2000Severe combined immunodeficiency–X1 (SCID-X1) is an X-linked inherited disorder characterized by an early block in T and natural killer (NK) lymphocyte differentiation. This block is caused by mutations of the gene encoding the γc cytokine receptor subunit of interleukin-2, -4, -7, -9, and -15 receptors, which participates in the delivery ...
M. Cavazzana‐Calvo +12 more
semanticscholar +3 more sources
The Case for Mandatory Newborn Screening for Severe Combined Immunodeficiency (SCID)
Journal of Clinical Immunology, 2014Severe combined immunodeficiency (SCID) is the most severe form of inherited primary immunodeficiency and is a paediatric emergency. Delay in recognising and detecting SCID can have fatal consequences and also reduces the chances of a successful haematopoietic stem cell transplant (HSCT).
H. Gaspar +6 more
semanticscholar +3 more sources
Human Taenia in Severe Combined Immunodeficiency (SCID) Mice
Parasitology Today, 1999A rodent model for the development of the larval stages of human taeniid tapeworms would help advance immunodiagnosis in human and domestic animals and vaccine development for cysticercosis cellulosae or bovis in domestic animals. Here, Akira Ito and Mamoru Ito review recent results demonstrating the potential of the severe combined immunodeficiency ...
A, Ito, M, Ito
openaire +2 more sources
Bacille Calmette-Guerin (BCG) complications in children with severe combined immunodeficiency (SCID)
Infectious Diseases, 2019Background: Bacille Calmette-Guerin (BCG) is included in the routine vaccination program in Gaza and the West Bank. Although safe, complications can occur and include local, extra-regional and disseminated BCG infection.
G. Barkai +4 more
semanticscholar +1 more source
Cellular radiosensitivity in human severe-combined-immunodeficiency (SCID) syndromes
Radiotherapy and Oncology, 1997The aim of the work was to establish to what extent a variety of human severe-combined-immunodeficiency (SCID) disorders are associated with in vitro cellular hypersensitivity to ionizing radiation.A study was made of fibroblast strains established from individuals with adenosine deaminase deficiency, T(-)B(-) SCID, Omenn's syndrome and a SCID ...
A R, Sproston, C M, West, J H, Hendry
openaire +2 more sources
Lymphopenia and Severe Combined Immunodeficiency (SCID) - Think Before You Ink
The Indian Journal of Pediatrics, 2019Severe combined immunodeficiency (SCID) represents one of the most severe forms of Primary immunodeficiency (PID) disorders, characterized by T cell lymphopenia (TCL) and lack of cellular and humoral immune responses. However, not all patients with low T cell lymphocyte counts may have an abnormal T cell immunity and the observed TCL may be a temporary
Jahnavi, Aluri +7 more
openaire +2 more sources
LPS-inducible responses in severe combined immunodeficiency (SCID) mice
Journal of Endotoxin Research, 1995Lipopolysaccharide (LPS) is a potent bacterial product that has been shown to act on many different cell types both in vivo and in vitro. Injection of immunologically competent mice with LPS results in increased serum cytokine levels, followed by an array of pathophysiologic alterations that can ultimately lead to death. In this study, we examined the
L.A. Falk +4 more
openaire +1 more source