Results 231 to 240 of about 45,777 (283)

Strategies for Retrovirus-Based Correction of Severe, Combined Immunodeficiency (SCID)

2012
Severe combined immunodeficiencies (SCIDs) appear as optimal disease targets to challenge potential efficacy of gene therapy. Ex vivo, retrovirally mediated gene transfer into hematopoietic progenitor cells has been shown to provide sustained correction of two forms of SCID, that is, SCID-X1 and adenosine deaminase deficiencies.
Fischer A, Hacein-Bey-Abina S, Cavazzana-Calvo M.   +2 more
openaire   +2 more sources

[Newborn screening for severe combined immunodeficiencies (SCID) in Germany].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 2023
Patients with a severe combined immunodeficiency (SCID) harbor genetic mutations disrupting T cell immunity and hence suffer severe, life-threatening infections or manifestations of immune dysregulation within the first months of their life. The only cure is to correct their immune system, usually by means of hematopoietic stem cell transplantation ...
Sujal, Ghosh, Michael H, Albert, Fabian, Hauck, Manfred, Hönig, Catharina, Schütz, Ansgar, Schulz, Carsten, Speckmann   +6 more
openaire   +1 more source

The case for severe combined immunodeficiency (SCID) and T cell lymphopenia newborn screening: saving lives…one at a time

Immunologic research, 2020
J. Quinn, J. Orange, V. Modell, F. Modell   +3 more
semanticscholar   +1 more source

Split Chimerism in Three Patients Suffering from Severe Combined Immunodeficiency (SCID)

1980
Three children, suffering from SCID, were lacking a genotypically identical sibling. One of them demonstrated spontaneous graft-versus-host (GvH) reaction due to a maternofetal transfusion. They were transplanted with the marrow of the HLA-A-mismatched but otherwise identical mother (1), with that of the completely mismatched mother in the case of ...
D, Niethammer, S F, Goldmann, H D, Flad, P, Wernet, G, Stursberg, J, Colombani, T M, Fliedner, E, Kleihauer   +7 more
openaire   +2 more sources

Transplantation of Lymphoid Cells in Patients with Severe Combined Immunodeficiency (SCID)

1980
The effects of bone marrow or fetal lymphoid organ transplants in 15 patients with severe combined immunodeficiency disease are reported. The benefits and dangers inherent to the various transplantation strategies are discussed. Our studies indicate that, even in the group of patients with B cells, bone marrow transplantation may be the best procedure ...
C, Griscelli, A, Durandy, J L, Virelizier, D, Buriot   +3 more
openaire   +2 more sources

Multiplication of human-derivedPneumocystis carinii in severe combined immunodeficient (SCID) mice

Experientia, 1992
Clinically healthy SCID mice were infected intratracheally with Pneumocystis carinii (PC) of human origin. The data obtained provides unambiguous evidence that progressive multiplication of PC organisms of human origin takes place in the lungs of experimentally infected animals.
openaire   +2 more sources

BCGosis in Infants with Severe Combined ImmunoDeficiency (SCID)

The Indian Journal of Pediatrics, 2018
Pavani Chitamanni, Jagadeesh Anbazhagan, Narayanan Parameswaran, Saravanakumari Vijayakumar   +3 more
openaire   +2 more sources

Bubble Boy Disease/ Severe Combined Immunodeficiency (SCID)

2022
Y. Kusumo Adi Arji Atmanto, Asvin Nurulita, Uleng Bahrun   +2 more
openaire   +1 more source

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Boris Böll, Victoria Metaxa   +2 more
exaly  

Guidelines for Screening, Early Diagnosis and Management of Severe Combined Immunodeficiency (SCID) in India

Indian Journal of Pediatrics, 2016
M. Madkaikar, Jahnavi Aluri, Sudhir Gupta   +2 more
semanticscholar   +1 more source