Results 91 to 100 of about 93,039 (260)

Distinct 5′ UTR Requirements for Translation of the Bicistronic X/P mRNA Among Avian Orthobornaviruses

Microbiology and Immunology, EarlyView.
ABSTRACT Orthobornaviruses express X and the phosphoprotein (P) from a bicistronic X/P mRNA, and these proteins regulate polymerase activity. In mammalian orthobornaviruses, the 5′ untranslated region (5′ UTR) of the X/P mRNA controls the translational balance between X and P and thereby promotes efficient replication.
Meng‐Chi Wu, Takehiro Kanda, Ryo Komorizono, Madoka Sakai, Alexander Leacy, Leonardo Susta, Akiko Makino, Keizo Tomonaga   +7 more
wiley   +1 more source

Exacerbation of Anti‐Cytomegalovirus Immunity and Mobilization of γ9δ1 T Cells During the Acute Phase of Hepatitis E Virus Infection

Microbiology and Immunology, EarlyView.
ABSTRACT HEV causes chronic infections that are detrimental to immunocompromised patients. Previous studies showed alterations of γδ T cell subsets at the acute phase of HEV infection. To assess a possible role of CMV, we have examined the frequencies and responses to CMV and HEV of blood γδ T cell subsets from control donors and acute‐phase HEV ...
Marion Retailleau, Fanny Martini, Florence Abravanel, Nassim Kamar, Jacques Izopet, Eric Champagne   +5 more
wiley   +1 more source

Clinical profile and predictors of Severe Dengue disease : A study from South India

Caspian Journal of Internal Medicine, 2018
Background: Dengue is endemic and prevalent in tropical and sub-tropical countries including India and can cause significant mortality and morbidity. There are limited studies available on factors associated with severe dengue from India, to investigate ...
Vijay Kumar Agrawal, Saroj Kumar Prusty, Ch Santosh Reddy, Gangireddy Krishna Mohan Reddy, Rakesh Kumar Agrawal, VCS Srinivasarao Bandaru   +5 more
doaj  

Severe dengue categories as research endpoints-Results from a prospective observational study in hospitalised dengue patients.

PLoS Neglected Tropical Diseases, 2020
Severe dengue was perceived as one clinical disease entity until the WHO 2009 classification stratified it into severe vascular leakage, severe bleeding, and severe organ dysfunction.
Kerstin D Rosenberger, Neal Alexander, Eric Martinez, Lucy C S Lum, Carl-Erik Dempfle, Thomas Junghanss, Bridget Wills, Thomas Jaenisch, DENCO Clinical Study Group   +8 more
doaj   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source

Acute pancreatitis complicating severe dengue

Journal of Global Infectious Diseases, 2014
Dengue is an arthropod borne viral infection endemic in tropical and subtropical continent. Severe dengue is life threatening. Various atypical presentations of dengue have been documented. But we present a rare and fatal complication of severe dengue in
Vishakha Jain, O P Gupta, Tarun Rao, Siddharth Rao   +3 more
doaj   +1 more source

Is dengue more severe in immunocompromised children?

, 2021
Meena Haldorai, Debasish Sahoo, Aditya Gupta, Jagdish Prasad Meena, Rachna Seth   +4 more
openalex   +1 more source

Imperative for a health‐centred focus on climate change in radiology

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Summary Climate change negatively impacts individual and population‐level health through multiple pathways, including poor air quality, extreme heat and changes in infectious disease. These health effects will lead to higher health system and medical imaging utilisation.
Omar Taboun, Chloe DesRoche, Kate Hanneman   +2 more
wiley   +1 more source

Peptide Bbeta(15-42) preserves endothelial barrier function in shock [PDF]

, 2009
Loss of vascular barrier function causes leak of fluid and proteins into tissues, extensive leak leads to shock and death. Barriers are largely formed by endothelial cell-cell contacts built up by VE-cadherin and are under the control of RhoGTPases. Here
Atrasheuskaya, Alena, Bukin, Eugenij, Friedl, Peter, Gröger, Marion, Hofer-Warbinek, Renate, Ignatyev, George, Knapp, Sylvia, Matt, Ulrich, Pasteiner, Waltraud, Petzelbauer, Peter, Reingruber, Sonja, Zacharowski, Kai, Zinkl, Daniela   +12 more
core  

Dengue encephalitis – An unusual case series

Journal of Family Medicine and Primary Care
Dengue infection can take on many different forms, ranging from no symptoms to a mild fever, all the way to a severe condition known as dengue shock syndrome.
Saniya Khosla, Rahul Chauhan, Ayush Aggarwal, Nupur B. Patel   +3 more
doaj   +1 more source