Immunogenicity of NS4b dengue 3 virus mimotope presented to the immune system as multiple antigen peptide system [PDF]
The availability of random peptide libraries displayed on bacteriophage (RPL) has provided a powerful tool for selecting sequences that mimic binding properties of natural antigen epitopes (mimotopes). These mimotopes can be used for vaccine design, drug
Acosta, Armando +11 more
core +2 more sources
Severe Dengue with Hemophagocytosis Syndrome.
Dengue is known to cause high morbidity and mortality worldwide. In recent years, there have been increasing cases of dengue fever associated with a rare complication: hemophagocytic syndrome (HPS), which is a dangerous disorder that carries high mortality. It is associated with infections, autoimmune disorders, and malignancies.
Siti Hartini Ishak +2 more
openaire +2 more sources
The impacts of biological invasions
ABSTRACT The Anthropocene is characterised by a continuous human‐mediated reshuffling of the distributions of species globally. Both intentional and unintentional introductions have resulted in numerous species being translocated beyond their native ranges, often leading to their establishment and subsequent spread – a process referred to as biological
Phillip J. Haubrock +42 more
wiley +1 more source
Optimal control of a dengue epidemic model with vaccination [PDF]
We present a SIR+ASI epidemic model to describe the interaction between human and dengue fever mosquito populations. A control strategy in the form of vaccination, to decrease the number of infected individuals, is used.
Delfim F. M. Torres +3 more
core +2 more sources
Spatiotemporal patterns and climatic drivers of severe dengue in Thailand.
OBJECTIVES The burden of dengue fever in Thailand is considerable, yet there are few large-scale studies exploring the drivers of transmission. This study aimed to investigate the spatiotemporal patterns and climatic drivers of severe dengue in Thailand.
Zhiwei Xu +8 more
semanticscholar +1 more source
Presentation and Management of Addison's Disease in a 10‐Year‐Old Boy: A Case Report
ABSTRACT Addison's disease, or primary adrenal insufficiency, is a rare endocrine disorder characterized by impaired adrenal hormone production. We report a case of a 10‐year‐old boy with congenital adrenal hyperplasia and secondary Addison's disease on long‐term corticosteroid therapy who presented with recurrent non‐bilious vomiting, low‐grade fever,
Srinivasan Sivannan +4 more
wiley +1 more source
Dengue Burden and Factors Influencing Severity in Honduras: A Descriptive and Analytical Study [PDF]
Background: Dengue is a disease that accounts for a major morbidity and mortality in Honduras. Methods: This descriptive study used an analytical component based on the data from the National Virology Laboratory between 2016-2022.
Melba Zúniga-Gutiérrez +6 more
doaj +1 more source
Impact of Comorbid Conditions on Severity of Dengue Fever: A Comparative Study
Objective: to identify the comorbid conditions associated with an increased risk of severe Dengue in clinically diagnosed patients with Dengue viral infections. Study Design: Comparative cross sectional study.
Amna Ashraf +5 more
doaj +1 more source
Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley +1 more source
Climate change vulnerability and adaptation assessment for Fiji [PDF]
All nations, including Fiji, that are signatories to the United Nations Framework Convention on Climate Change(UNFCCC) are obliged to provide National Communications to the Conference of Parties (COP) of the UNFCCC. The COP4 stressed the need for parties
Bhusan, Jagat +5 more
core +1 more source

