Results 71 to 80 of about 1,676,317 (259)

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source

Evaluation of the performance of a dengue outbreak detection tool for China [PDF]

, 2014
An outbreak detection and response system, using time series moving percentile method based on historical data, in China has been used for identifying dengue fever outbreaks since 2008.
Wang, Liping, Yang, Weizhong, Clements, Archie C.A., Shengjie Lai, Hu, Wenbiao, Wenwu Yin, Yin, Wenwu, Hang Zhou, Zhou, Hang, Archie C A Clements, Archie C. A. Clements, Li, Zhongjie, Yu, Hongjie, Zhongjie Li, Lai, Shengjie, Weizhong Yang, Wenbiao Hu, Zhang, Honglong, Hongjie Yu, Clements, Archie C. A., Liping Wang, Honglong Zhang   +21 more
core   +1 more source

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

Acta Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source

Factors predicting severe dengue in patients with dengue Fever.

Mediterranean journal of hematology and infectious diseases, 2013
Dengue virus (DENV) affects over half the world's population in 112 countries, and dengue fever (DF) is the second largest arthropod borne infectious global hazard after malaria with complications like Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS), accounting for significant morbidity and mortality world-over. Pakistan is significantly
Khan, Muhammad Imran Hasan, Anwar, Eram, Agha, Adnan, Hassanien, Noha Saleh Mohamed, Ullah, Ehsan, Syed, Imran Ali, Raja, Arsalan   +6 more
openaire   +2 more sources

Spontaneous calf haematoma in severe dengue [PDF]

BMJ Case Reports, 2018
We report a case of spontaneous calf muscle haematoma, formed during the recovery phase of dengue haemorrhagic fever, which, to the best of our knowledge, has never been encountered before. A 45-year-old man presented with features of severe dengue and got admitted to our intensive care unit. He was treated with intravenous fluid therapy and supportive
Ahmad Mursel, Anam, Raihan, Rabbani, Farzana, Shumy   +2 more
openaire   +2 more sources

Trained Immunity in Childhood Vaccination

Acta Paediatrica, EarlyView.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai, Lubnaa Hossenbaccus, Eva Kaufmann   +2 more
wiley   +1 more source

Frayed Rope and Resilient Threads: Fijian Healthcare and the COVID‐19 Pandemic

Asia Pacific Viewpoint, EarlyView.
ABSTRACT In April 2021, Fiji faced international scrutiny due to ‘horrific’ hospital conditions, including staff and patients lacking food, non‐operational operating theatres, and critical shortages of beds, medicine, and equipment. After successfully avoiding a major outbreak in 2020, a sudden surge in COVID‐19 cases in 2021 overwhelmed the public ...
Sharon McLennan, Johanna Thomas‐Maude, Apisalome Movono, Akisi Ravono   +3 more
wiley   +1 more source

Dengue severity in the elderly in Puerto Rico [PDF]

Revista Panamericana de Salud Pública, 2003
Severe dengue affects all age groups in the Americas, but little detailed information is available about this disease in the elderly. The objective of this article is to describe the disease in this age group.We reviewed suspected dengue-case investigation forms submitted with diagnostic samples as well as clinical reports from infection control nurses
Enid J, García-Rivera, José G, Rigau-Pérez   +1 more
openaire   +2 more sources

Health Research Funders and Justice: Obligations to Coordinate and Counterbalance

Bioethics, EarlyView.
ABSTRACT Government health research funders are frequently criticized on the grounds that their distribution of resources fails to reflect a population's disease burden. These critiques do not take into account what other research funders are doing. In this paper, I argue that this is a mistake.
Joseph Millum
wiley   +1 more source

Severe Dengue Fever Outbreak in Taiwan [PDF]

The American Society of Tropical Medicine and Hygiene, 2016
Dengue fever (DF) is a vector-borne disease caused by dengue viruses (DENVs). Epidemic dengue occurs intermittently in Taiwan. In 2014, Taiwan experienced its largest DF outbreak. There were 15,732 DF cases reported. There were a total of 136 dengue hemorrhagic fever (DHF) cases, of which 20 resulted in death.
Sheng-Fan, Wang, Wen-Hung, Wang, Ko, Chang, Yen-Hsu, Chen, Sung-Pin, Tseng, Chia-Hung, Yen, Deng-Chyang, Wu, Yi-Ming Arthur, Chen   +7 more
openaire   +2 more sources