Results 101 to 110 of about 90,481 (291)
Diagnosis and Prognosis of Severe Dengue [PDF]
, 2011 Dengue has a broad spectrum of clinical symptoms, ranging from asymptomatic infection, undifferentiated fever and dengue fever (DF) to dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). DHF and DSS are the most severe forms of the disease, as they involve bleeding and hypovolemic shock and may lead to death if they are not diagnosed early ...
openaire +2 more sources
ChemistryOpen, EarlyView.A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados +9 more
wiley +1 more source
People and Nature, EarlyView.Abstract There is growing interest in using urban greening projects to support biodiversity. While there are many potential co‐benefits, the health outcomes resulting from biodiversity‐supporting activities have yet to be synthesized. We conducted a systematic review of health outcomes associated with seven biodiversity‐supporting elements, including ...
Erica N. Spotswood +19 more
wiley +1 more source
Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Accurate biomolecular structure prediction enables the prediction of mutational effects, the speculation of function based on predicted structural homology, the analysis of ligand binding modes, experimental model building, and many other applications.
Rachael C. Kretsch +32 more
wiley +1 more source
Clinical profile and predictors of Severe Dengue disease : A study from South India
Caspian Journal of Internal Medicine, 2018 Background: Dengue is endemic and prevalent in tropical and sub-tropical countries including India and can cause significant mortality and morbidity. There are limited studies available on factors associated with severe dengue from India, to investigate ...
Vijay Kumar Agrawal +5 more
doaj
Microbiology and Immunology, EarlyView.ABSTRACT Seasonal influenza is prevalent every winter, and influenza vaccines are used to safeguard public health. As the influenza vaccines are produced in embryonated hen eggs using vaccine viruses recommended by the World Health Organization each year based on the epidemic situation, it is important, from the perspective of public health, to ...
Kayoko Sato +12 more
wiley +1 more source
Risk factors associated with death in Brazilian children with severe dengue: a case-control study
Clinics, 2014 Objective: The purpose of this case-control study was to evaluate risk factors associated with death in children with severe dengue. Methods: The clinical condition of hospitalized patients with severe dengue who died (cases, n = 18) was compared with ...
Maria dos Remedios Freitas Carvalho Branco +12 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2020 Severe dengue was perceived as one clinical disease entity until the WHO 2009 classification stratified it into severe vascular leakage, severe bleeding, and severe organ dysfunction.
Kerstin D Rosenberger +8 more
doaj +1 more source
Enhancement of Epidemiological Models for Dengue Fever Based on Twitter Data
, 2017 Epidemiological early warning systems for dengue fever rely on up-to-date epidemiological data to forecast future incidence. However, epidemiological data typically requires time to be available, due to the application of time-consuming laboratorial ...
Albinati, Julio +4 more
core +1 more source
Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Insect Science, EarlyView.Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source