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Knowledge gaps in the epidemiology of severe dengue impede vaccine evaluation.

Lancet. Infectious Diseases (Print), 2021
The most severe consequences of dengue virus infection include shock, haemorrhage, and major organ failure; however, the frequency of these manifestations varies, and the relative contribution of pre-existing anti-dengue virus antibodies, virus ...
Tyler M. Sharp   +8 more
semanticscholar   +1 more source

Establishment of SMS Dengue Severity Score

Journal of the Association of Physicians of India, 2022
Background: Dengue infection is a disease that progresses rapidly to life-threatening conditions. Our goal was to develop a practical scoring system based on clinical profiles and routine tests to predict the severity of infection. Methods: This cross-sectional observational study included 500 patients with dengue infection.
Sudhir, Bhandari   +5 more
openaire   +2 more sources

Risk factors and biomarkers of severe dengue.

Current Opinion in Virology, 2020
Dengue virus infects several million people each year. Although usually a self-limiting disease, some patients can develop life-threatening severe complications, characterized by plasma leakage, hemorrhaging, and shock.
Abhay P. S. Rathore   +2 more
semanticscholar   +1 more source

Ferritin levels predict severe dengue

Infection, 2014
Currently, no tests are available to monitor and predict severity and outcome of dengue. To find potential markers that predict dengue severity, the present study validated the serum level of three acute-phase proteins α-1 antitrypsin, ceruloplasmin and ferritin in a pool of severe dengue cases compared to non-severe forms and other febrile illness ...
R, Soundravally   +4 more
openaire   +2 more sources

Severe dengue and liver involvement: an overview and review of the literature

Expert Review of Anti-Infective Therapy, 2020
Introduction Two billion population are at risk of dengue fever and by 2080, over six billion population will be at risk. Hepatitis is common in dengue and the liver is invariably involved in severe cases.
P. Chia   +4 more
semanticscholar   +1 more source

Unusual, neurological and severe dengue manifestations during the outbreak in Sri Lanka, 2017.

Journal of Clinical Virology, 2020
BACKGROUND Sri Lanka experienced its largest dengue outbreak in 2017 with more than 185,000 dengue cases including at least 250 fatalities. OBJECTIVES Our study aimed to characterize the clinical, immunological and virological features of confirmed ...
Mya Myat Ngwe Tun   +12 more
semanticscholar   +1 more source

Markers of Dengue Disease Severity

2009
Infection with one of the four serotypes of dengue virus (DENV) causes a wide spectrum of clinical disease ranging from asymptomatic infection, undifferentiated fever, dengue fever (DF) to dengue hemorrhagic fever (DHF). DHF occurs in a minority of patients and is characterized by bleeding and plasma leakage which may lead to shock. There are currently
Anon, Srikiatkhachorn, Sharone, Green
openaire   +2 more sources

Severe Dengue Prognosis Using Human Genome Data and Machine Learning

IEEE Transactions on Biomedical Engineering, 2019
Dengue has become one of the most important worldwide arthropod-borne diseases. Dengue phenotypes are based on laboratorial and clinical exams, which are known to be inaccurate.
C. Davi   +8 more
semanticscholar   +1 more source

Severe dengue: questioning the paradigm

Microbes and Infection, 2010
Severe dengue has been recognised for more than 200 years, but attempts to define, categorize and explain the condition have hotly contested for more than four decades. Resolution of this controversy may provide new insights for the management of patients.
openaire   +2 more sources

CORRELATION OF DENGUE SCORE WITH THE SEVERITY OF DENGUE

GLOBAL JOURNAL FOR RESEARCH ANALYSIS, 2023
Background : Dengue is one of the most prevalent vector borne diseases worldwide. Dengue fever presents with wide clinical spectrum ranging from self limiting infection to severe dengue. Aim: Present study is done to correlate a novel indicator 'Dengue Score' with the severity of dengue.
Hemachandra P, Sharath N, Swathi Maiya
openaire   +1 more source

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