Results 71 to 80 of about 91,699 (304)

Optimal control of a dengue epidemic model with vaccination [PDF]

, 2011
We present a SIR+ASI epidemic model to describe the interaction between human and dengue fever mosquito populations. A control strategy in the form of vaccination, to decrease the number of infected individuals, is used.
Delfim F. M. Torres, Helena Sofia Rodrigues, M. Teresa, T. Monteiro   +3 more
core   +2 more sources

Severe Dengue with Hemophagocytosis Syndrome.

Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia, 2020
Dengue is known to cause high morbidity and mortality worldwide. In recent years, there have been increasing cases of dengue fever associated with a rare complication: hemophagocytic syndrome (HPS), which is a dangerous disorder that carries high mortality. It is associated with infections, autoimmune disorders, and malignancies.
Siti Hartini Ishak, Lili Husniati Yaacob, Azlina Ishak   +2 more
openaire   +2 more sources

Biomarkers of severe dengue disease – a review [PDF]

Journal of Biomedical Science, 2015
Dengue virus infection presents a wide spectrum of manifestations including asymptomatic condition, dengue fever (DF), or severe forms, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) in affected individuals. The early prediction of severe dengue in patients without any warning signs who may later develop severe DHF is very ...
John, Daisy Vanitha, Lin, Yee-Shin, Perng, Guey Chuen   +2 more
openaire   +2 more sources

Plant Virus‐Induced Inheritable Apoptosis Drives Reproductive Costs in Female Insect Vectors to Balance Viral Biparental Transmission

Advanced Science, EarlyView.
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu, Wenqiang Wan, Qingquan Liang, Hengsong Yang, Chengcong Lu, Taiyun Wei, Qian Chen   +6 more
wiley   +1 more source

The Zika outbreak of the 21st century. [PDF]

, 2016
The Zika virus outbreak has captivated the attention of the global audience and information has spread rapidly and wildly through the internet and other media channels.
Ansari, Aftab, Chang, Christopher, Gershwin, M Eric, Ortiz, Kristina   +3 more
core   +1 more source

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source

Analyses of clinical and laboratory characteristics of dengue adults at their hospital presentations based on the World Health Organization clinical-phase framework: Emphasizing risk of severe dengue in the elderly

Journal of Microbiology, Immunology and Infection, 2018
Background/Purpose: Dengue clinically dynamically changes over time; the World Health Organization (WHO) dengue classification framework proposed 3 dengue clinical phases—febrile (days 1–3), critical (days 4–6) and recovery (days ≥7) phases.
Hong-Jie Kuo, Ing-Kit Lee, Jien-Wei Liu
doaj   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

Advanced Science, EarlyView.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu, Guigen Zhang, Yuan Lin, Shiming Yi, Jingyu Yang, Xueying Lin, Deli Song, Zhiheng Liu, Jiayu Zhang, Ying Zeng, Shanyu Huang, Zhen Fan, Jifu Zhang, Ying Liu, Cheng Hu, Wenbo Zhu, Wei Yin, Jun Hu, Guangmei Yan, Jing Cai, Jiankai Liang   +20 more
wiley   +1 more source

Implications of discordance in world health organization 1997 and 2009 dengue classifications in adult dengue. [PDF]

PLoS ONE, 2013
BACKGROUND: Revised dengue guidelines were published by the World Health Organization (WHO) in 2009 addressing severe dengue cases not classified by dengue hemorrhagic fever (DHF) and shock syndrome (DSS).
Victor C Gan, David C Lye, Tun L Thein, Frederico Dimatatac, Adriana S Tan, Yee-Sin Leo   +5 more
doaj   +1 more source

Impact of Comorbid Conditions on Severity of Dengue Fever: A Comparative Study

Pakistan Armed Forces Medical Journal, 2023
Objective: to identify the comorbid conditions associated with an increased risk of severe Dengue in clinically diagnosed patients with Dengue viral infections. Study Design: Comparative cross sectional study.
Amna Ashraf, Sana Zafar, Faisal Mehmood, Karamat Hussain Shah Bukhari, Aamir Habib, Muhammad Ammar Husnain   +5 more
doaj   +1 more source