How Real-World Mepolizumab Users in the REALITI-A Study Relate to the Recruitment Criteria Applied in the Randomized, Placebo-Controlled Trials of Subcutaneous Mepolizumab in Severe Eosinophilic Asthma [PDF]
, 2021 David Ramos‐Barbón +12 more
openalex +1 more source
Allergy, EarlyView.ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga +7 more
wiley +1 more source
Efficacy of mepolizumab for patients with severe asthma and eosinophilic chronic rhinosinusitis [PDF]
, 2019 Takanori Numata +10 more
openalex +1 more source
COVID-19, Eosinophils, and Biologicals for Severe Asthma
Frontiers in Allergy, 2022 Lombardi, Carlo +2 more
openaire +3 more sources
Allergy, EarlyView.Two‐year data of tapered dupilumab shows high effectiveness in CRSwNP with NSAID‐exacerbated respiratory disease. We assessed whether dupilumab is equally effective in CRSwNP with NSAID‐exacerbated respiratory disease (N‐ERD) patients as in CRSwNP patients without N‐ERD (CRSwNP‐NOS; not otherwise specified).
H. B. E. Elzinga +17 more
wiley +1 more source
TNF Superfamily and ILC2 Activation in Asthma
BiomoleculesEosinophilic asthma is the most prevalent and well-defined phenotype of asthma. Despite a majority of patients responding to corticosteroid therapy and T2 biologics, there remains a subset that have recurrent asthma exacerbations, highlighting a need for
Takahiro Matsuyama +4 more
doaj +1 more source
Successful management of severe asthma in a young boy with eosinophilic chronic rhinosinusitis who received omalizumab: a case report [PDF]
, 2019 Yasuho Shoda +7 more
openalex +1 more source
COVID-19 in a Patient With Severe Eosinophilic Asthma on Benralizumab Therapy: A Case Report and Review of Literature [PDF]
, 2021 Osamu Matsuno, Seijiro Minamoto
openalex +1 more source
Childhood Asthma and Allergy Are Related to Accelerated Epigenetic Aging
Allergy, EarlyView.We used a pediatric epigenetic clock to assess epigenetic age in children from a German birth cohort. Accelerated epigenetic aging was found to be related to the presence of allergic diseases like asthma, rhinitis, or eczema, but not to non‐symptomatic aeroallergen sensitization. This was supported by an epigenetic age acceleration gradient in response
Miriam Leskien +11 more
wiley +1 more source
Level of Eosinophil Cationic Protein in Sputum of Chemical Warfare Victims [PDF]
Objective(s) Considering fair response to inhaled corticosteroids and reports of severe air way hyper responsiveness in chemical warfare victims (CWV), a role for eosinophilic inflammation (i.e. asthma) was postulated.
توحیدی, محمد +7 more
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