Results 231 to 240 of about 1,917,601 (292)

Efficacy of benralizumab in reducing cough and/or dyspnea frequency, and improving cough-specific health-related quality of life in patients with severe eosinophilic asthma in Asia. [PDF]

Ther Adv Respir Dis
Lai K, Sun D, Dai R, Xu X, Zhao J, Wu T, Ho CN, Werkström V, Cohen D, Necander S, Zhong N.   +10 more
europepmc   +1 more source

Mechanism of Pingchuanning in Attenuating Asthma Based on UHPLC‐Q‐Orbitrap HRMS and Network Pharmacology Analysis

Biomedical Chromatography, Volume 40, Issue 12, December 2026.
ABSTRACT An ultrahigh‐performance liquid chromatography coupled with quadrupole‐Orbitrap high‐resolution mass spectrometry (UHPLC‐Q‐Orbitrap HRMS) method was applied to characterize Pingchuanning (PCN) decoction and its absorbed serum constituents in asthmatic rats.
Yue Zhang, Yiwen Ding, Weidong Chen, Yuanbo Bi, Yanyan Wang, Weidong Ye, Xiangming Fang   +6 more
wiley   +1 more source

Cytokine and Metabolomic Signatures of Mepolizumab Response Across Upper and Lower Airway Compartments in Severe Eosinophilic Asthma: An Exploratory Analysis. [PDF]

Pharmaceuticals (Basel)
Maniscalco M, Ambrosino P, Candia C, Di Stefano A, Gnemmi I, Zappa M, Ambrosino N, Visca D, Motta A.   +8 more
europepmc   +1 more source

No Effect of Preoperative Mepolizumab on Early Postoperative Healing After ESS for Severe CRSwNP

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 6, December 2026.
ABSTRACT Objective To evaluate postoperative endoscopic mucosal healing 2 weeks after ESS in patients with severe CRSwNP treated with surgery alone versus surgery combined with biologics initiated 2 weeks preoperatively. Methods In this exploratory post hoc analysis, patients with severe CRSwNP were divided into two cohorts: ESS alone and ESS with ...
A. S. Homøe, M. Høxbro, J. Tidemandsen, V. Backer, E. Kiaer, S. Scott, N. Rubek, K. Aanæs   +7 more
wiley   +1 more source

Benralizumab and the integrated management of co-morbid severe eosinophilic asthma with chronic rhinosinusitis with nasal polyps. [PDF]

Clin Transl Allergy
Mullol J, D'Amato M, de Corso E, Han JK, Tversky J.   +4 more
europepmc   +1 more source

Health‐Care Burden of Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Hong Kong in the Post‐COVID Pandemic Era—Impact of Phenotype and Exacerbation History

Public Health Challenges, Volume 5, Issue 4, December 2026.
There was an increase in the AECOPD admission numbers after the COVID‐19 pandemic, resulting in increase in health economic burden. ABSTRACT Rationale Chronic obstructive pulmonary disease (COPD) is known to be associated with substantial health‐care utilization and economic costs.
Wang Chun Kwok, Ali Choo, Lu Zhou, Ting Fung Ma, Isaac Sze Him Leung, Chun Ka Wong, James Chung Man Ho   +6 more
wiley   +1 more source

Population Pharmacokinetics and Exposure-Response Analysis of Benralizumab in Chinese Adults, Adolescents, and Pediatric Participants with Severe Eosinophilic Asthma. [PDF]

Clin Pharmacokinet
Jin Y, Guiastrennec B, Stuke M, Yao Y, Zhang Y, Barker P, Jison M, Penland RC, Ding J, Lukka PB.   +9 more
europepmc   +1 more source

Clinical Effects of Adjunctive Shoseiryuto Therapy in Refractory Eosinophilic Chronic Rhinosinusitis: A Pilot Retrospective Case Series Focusing on Mucus‐Related Symptoms

Traditional &Kampo Medicine, Volume 13, Issue 3, December 2026.
ABSTRACT Aim To evaluate the efficacy and safety of adjunctive shoseiryuto, a traditional Japanese Kampo medicine, in patients with refractory eosinophilic chronic rhinosinusitis (ECRS), with particular attention to mucus‐related symptoms. Methods This retrospective pilot case series was conducted at Osaka Medical and Pharmaceutical University Hospital
Yusuke Kikuoka
wiley   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, Volume 117, Issue 6, Page 1485-1499, December 2026.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source