Results 211 to 220 of about 23,640 (262)

The economic burden of asthma in Italy: evaluating the potential impact of different treatments in adult patients with severe eosinophilic asthma. [PDF]

Eur J Health Econ
Scortichini M, Mennini FS, Marcellusi A, Paoletti M, Tomino C, Sciattella P.   +5 more
europepmc   +1 more source

Long-Term Eosinophil Depletion: A Real-World Perspective on the Safety and Durability of Benralizumab Treatment in Severe Eosinophilic Asthma. [PDF]

J Clin Med
Menzella F, Marchi M, Caminati M, Romagnoli M, Micheletto C, Bonato M, Idotta G, Nizzetto M, D'Alba G, Cavenaghi M, Bortoli M, Beghè B, Pini L, Benoni R, Casoni G, Muzzolon R, Michieletto L, Bosi A, Mastrototaro A, Diamandi A, Nalin M, Senna G.   +21 more
europepmc   +1 more source

Case Report: Dual monoclonal antibody therapy in chronic rhinosinusitis with nasal polyps and severe eosinophilic asthma-a proteome analysis. [PDF]

Front Allergy
Blauwblomme M, Gevaert P, Van Nevel S, Riemann S, Vandewalle E, Holtappels G, De Ruyck N, Derycke L, Eeckels AS, Vanhee S, Lambrecht BN, Brusselle G, Van Zele T.   +12 more
europepmc   +1 more source

Effects of benralizumab in patients with severe eosinophilic asthma (SEA): A plain language summary of the ANANKE study. [PDF]

Immunotherapy
Canonica GW, Consani L, Malerba L, Pelaia G, Vultaggio A, ANANKE investigators.   +5 more
europepmc   +1 more source

SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma. [PDF]

Int J Mol Sci
Rojo-Tolosa S, Sánchez-Martínez JA, Caballero-Vázquez A, Pineda-Lancheros LE, González-Gutiérrez MV, Pérez-Ramírez C, Jiménez-Morales A, Morales-García C.   +7 more
europepmc   +1 more source

Assessment of MUcociLiary Transport timE in CRSwNP Patients in Treatment With Dupilumab: AMULET Study

International Forum of Allergy &Rhinology, Volume 16, Issue 8, Page 886-888, August 2026.
Alessia Giorli, Fabio Ferretti, Antonio Romano, Marco Casiraghi, Mariella Scarano, Paolo Farneti, Giacomo Sollini, Marco Mandalà, Ernesto Pasquini, Cesare Biagini   +9 more
wiley   +1 more source

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Clusters of Severe Eosinophilic Asthma in a Korean Asthma Cohort

Respiration, 2021
<b><i>Background:</i></b> Targeted therapies have broadened the available treatment options for patients with severe eosinophilic asthma (SEA). However, differences in the magnitude of treatment responses among patients indicate the presence of various underlying pathophysiological processes and patient subgroups. <b><i&
Ji-Hyang Lee, Jin An, Ha-Kyeong Won, Bomi Seo, Jung-Hyun Kim, So-Young Park, Min-Hye Kim, Yoo Seob Shin, Jae-Woo Jung, Woo-Jung Song, Taehoon Lee, Hyouk-Soo Kwon, Jae Hyun Lee, Joo-Hee Kim, Sae-Hoon Kim, Yoon-Seok Chang, You Sook Cho, Dong-Ho Nahm, An-Soo Jang, Jung-Won Park, Ho-Joo Yoon, Sang-Heon Cho, Young-Joo Cho, Byoung Whui Choi, Hee-Bom Moon, Tae-Bum Kim   +25 more
openaire   +2 more sources

Mepolizumab in the Treatment of Severe Eosinophilic Asthma

Immunotherapy, 2015
IL-5 is crucial in the pathogenesis and evolution of eosinophilic asthma. Mepolizumab is a high-affinity humanized monoclonal antibody of the IgG1/k subtype that inhibits the binding of IL-5 to its receptor expressed on eosinophils, thereby inducing significant reduction in eosinophil circulation, as well as asthma exacerbations and corticosteroid ...
FAINARDI, Valentina, PISI, GIOVANNA, CHETTA, Alfredo Antonio   +2 more
openaire   +4 more sources

Eosinophils in the pathogenesis of paediatric severe asthma

Current Opinion in Allergy & Clinical Immunology, 2014
The importance and functional contribution of eosinophils to the pathogenesis of severe asthma was questioned when adult studies reported neutrophilic inflammation and Th17 cells were central to disease.Eosinophilic inflammation, atopic sensitization and airway remodelling are the hallmark features of severe asthma in children.
Sejal, Saglani, Clare M, Lloyd
openaire   +2 more sources