Results 271 to 280 of about 327,068 (394)

Dupilumab shows no elevated risk for maternal adverse pregnancy outcomes: A propensity‐matched cohort study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This large‐scale, propensity‐matched retrospective cohort study provides evidence that dupilumab treatment during pregnancy is not associated with an elevated risk of maternal adverse pregnancy outcomes (APOs). By utilizing real‐world data, it contributes critical insights into dupilumab's safety profile in pregnant women, addressing a crucial gap in ...
Sophie L. Preuß, Katja Bieber, Artem Vorobyev, Andreas Recke, Eva Lotta Moderegger, Henner Zirpel, Evelyn Gaffal, Diamant Thaçi, Khalaf Kridin, Ralf J. Ludwig   +9 more
wiley   +1 more source

Early and Sustained Clinical Benefits of Benralizumab in Severe Eosinophilic Asthma: Findings from the ORBE II Study. [PDF]

J Clin Med
Ausín P, Navarrete-Rouco ME, Carazo L, Sanchez-Trincado JL, Luzon E, Nuevo J, Santín M, Sánchez J, Padilla-Galo A.   +8 more
europepmc   +1 more source

The Milan Score is an Effective Manometric Tool to Predict Gastroesophageal Reflux in Patients With Laryngopharyngeal Symptoms

Neurogastroenterology &Motility, EarlyView.
Patients with isolated LPS demonstrated a lower likelihood of EGJ disruption, pathologic GERD, and abnormal Milan score. The Milan score performed similarly well in the identification of GERD in both LPS and typical symptoms. The Milan score could therefore be used as an upfront test in LPS patients.
Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Ivan Kristo, Nicola De Bortoli, Salvatore Tolone, Elisa Marabotto, Daniele Bernardi, Sebastian F. Schoppmann, Roberto Penagini, Benjamin Rogers, Anthony Hobson, Jordan Haworth, Brian Louie, Yeong Yeh Lee, Vincent Tee, Takahiro Masuda, Dimitrios Theodorou, Tania Triantafyllou, Benedetta Barcella, Lorenzo Cusmai, Michele Puricelli, Marina Coletta, Vito Annese, Edoardo Vincenzo Savarino, Emanuele Luigi Giuseppe Asti, C. Prakash Gyawali   +26 more
wiley   +1 more source

Effects of azithromycin in severe eosinophilic asthma with concomitant monoclonal antibody treatment. [PDF]

Thorax
Lavoie G, Howell I, Melhorn J, Borg C, Bermejo-Sanchez L, Seymour J, Jabeen MF, Fries A, Hynes G, Pavord ID, Petousi N, Hinks TS.   +11 more
europepmc   +1 more source

Characterization and Factors Associated with Poor Asthma Control in Adults with Severe Eosinophilic Asthma. [PDF]

J Pers Med, 2023
Padró-Casas C, Basagaña M, Rivera-Ortún ML, García-Olivé I, Pollan-Guisasola C, Teniente-Serra A, Martínez-Cáceres E, Navarro JT, Abad-Capa J, Rosell A, Roger A, Martínez-Rivera C.   +11 more
europepmc   +1 more source

Bronchiectasis in severe asthma is associated with eosinophilic airway inflammation and activation

, 2022
Laurits Frøssing, Anna von Bülow, Celeste Porsbjerg   +2 more
openalex   +1 more source

Contemporary Concise Review 2024: Chronic Obstructive Pulmonary Disease

Respirology, EarlyView.
SUMMARY OF KEY POINTS Non‐smoking COPD is common in LMICs, especially in women. Biomass fuel and air pollution are major risk factors with distinct pathophysiology. The ‘eosinophilic’ endotype in COPD is biologically distinct from asthma. PRISm, FEV1/FVC Z‐scores, and quantitative CT improve early COPD detection.
Sarita Thawanaphong, Parameswaran Nair
wiley   +1 more source

The Effect of Mepolizumab on Blood Eosinophil Subtype Distribution and Granule Protein Gene Expression in Severe Eosinophilic Asthma. [PDF]

J Asthma Allergy
Rimkunas A, Januskevicius A, Vasyle E, Palacionyte J, Kalinauskaite-Zukauske V, Miliauskas S, Malakauskas K.   +6 more
europepmc   +1 more source

Eosinophilic Sialodochitis: A Rare Comorbidity of Severe Asthma

Journal of Investigational Allergy and Clinical Immunology, 2023
O, González, C, Picado, E, Arismendi, I, Alobid, J, Ramirez, A, Valero, I, Bobolea   +6 more
openaire   +2 more sources

ILC2 Diversity, Location, and Function in Pulmonary Disease

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma, Uryan I. Can, R. Lee Reinhardt   +2 more
wiley   +1 more source