Results 81 to 90 of about 327,068 (394)

Sputum autoantibodies in patients with severe eosinophilic asthma [PDF]

Journal of Allergy and Clinical Immunology, 2018
The persistence of eosinophils in sputum despite high doses of corticosteroids indicates disease severity in asthmatic patients. Chronic inflamed airways can lose tolerance over time to immunogenic entities released on frequent eosinophil degranulation, which further contributes to disease severity and necessitates an increase in maintenance ...
Sergei I. Ochkur, Parameswaran Nair, Melanie Kjarsgaard, James B. Mahony, Chynna Margaret Huang, David Bulir, Paige Lacy, Katherine Radford, Elizabeth A. Jacobsen, Ana Catuneanu, Hanah Lamothe-Kipnes, Manali Mukherjee, James J. Lee   +12 more
openaire   +3 more sources

Building a Decision Support System for Automated Mobile Asthma Monitoring in Remote Areas [PDF]

arXiv, 2021
Advances in mobile computing have paved the way for the development of several health applications using smartphone as a platform for data acquisition, analysis and presentation. Such areas where mhealth systems have been extensively deployed include monitoring of long term health conditions like Cardio Vascular Diseases and pulmonary disorders, as ...
arxiv  

Eosinophilic bronchitis, eosinophilic granuloma, and eosinophilic bronchopneumopathy in 75 dogs (2006-2016). [PDF]

, 2019
BackgroundEosinophilic lung disease is a poorly understood inflammatory airway disease that results in substantial morbidity.ObjectiveTo describe clinical findings in dogs with eosinophilic lung disease defined on the basis of radiographic, bronchoscopic,
Dear, Jonathan D, Hulsebosch, Sean E, Johnson, Eric G, Johnson, Lynelle R, Vernau, William   +4 more
core   +1 more source

Organization, Clinical and Management Indicators on the First Year of Activity of an Outpatient Clinic Dedicated to the Diagnosis and Treatment of Severe Asthma in Italy

Journal of Asthma and Allergy, 2021
Silvia Tognella,1 Claudio Micheletto,2 Alessandro Roggeri,3 Guido Polese,4 Denise Artioli,1 Gianenrico Senna,5 Marco Caminati,5,6 Daniela Paola Roggeri3 1Pulmonology Unit, Mater Salutis Hospital, Legnago (Verona), Italy; 2Pulmonology Unit, Azienda ...
Tognella S, Micheletto C, Roggeri A, Polese G, Artioli D, Senna G, Caminati M, Roggeri DP   +7 more
doaj  

New therapy options for patients with eosinophilic type of severe bronchial asthma

Медицинский совет, 2020
The article provides data on the epidemiology of severe asthma. It defines the phenotype and endotype of bronchial asthma and classifies BA according to phenotype/endotype.
G. L. Ignatova, V. N. Antonov, E. V. Blinova, I. V. Grebneva, E. V. Sheklanova   +4 more
doaj   +1 more source

Cytokine and Lipid Mediator Regulation of Group 2 Innate Lymphoid Cells (ILC2s) in Human Allergic Airway Disease. [PDF]

, 2017
The recent discovery of group 2 innate lymphoid cells (ILC2s) has caused a paradigm shift in the understanding of allergic airway disease pathogenesis.
Cavagnero, Kellen, Doherty, Taylor A
core   +2 more sources

Sustained remission induced by 2 years of treatment with benralizumab in patients with severe eosinophilic asthma and nasal polyposis

Respirology (Carlton South. Print)
Several randomized controlled trials (RCTs) have shown that benralizumab is characterized by a good profile of efficacy and safety, thereby being potentially able to elicit clinical remission on‐treatment of severe eosinophilic asthma (SEA).
C. Pelaia, C. Crimi, A. Benfante, M. Caiaffa, R. Campisi, Claudio Candia, G. E. Carpagnano, Isabella Carrieri, Maria D'amato, Aikaterini Detoraki, M. P. F. Barbaro, N. Lombardo, L. Macchia, A. Maglio, Elena Minenna, S. Nolasco, Giuseppe Paglino, F. Papia, Luisa Ricciardi, Nicola Scichilone, Giulia Scioscia, G. Spadaro, P. Tondo, Simona Uletta Lionetti, G. Valenti, A. Vatrella, N. Crimi, G. Pelaia   +27 more
semanticscholar   +1 more source

Clinical usefulness of mepolizumab in severe eosinophilic asthma

Therapeutics and Clinical Risk Management, 2016
Asthma is a chronic inflammatory disorder of the airways with variable clinical severity from very mild and occasional symptoms to recurrent critical exacerbations, at risk of fatal or near-fatal outcome, in a small percentage of patients. Within the different inflammatory cascades involved in asthma, eosinophils play a central role in the pathogenesis
Nicola Facciolongo, Luigi Zucchi, Mirco Lusuardi, Francesco Menzella, Gloria Montanari, Carla Galeone   +5 more
openaire   +5 more sources

Harnessing Digital Pathology And Causal Learning To Improve Eosinophilic Esophagitis Dietary Treatment Assignment [PDF]

arXiv, 2023
Eosinophilic esophagitis (EoE) is a chronic, food antigen-driven, allergic inflammatory condition of the esophagus associated with elevated esophageal eosinophils. EoE is a top cause of chronic dysphagia after GERD. Diagnosis of EoE relies on counting eosinophils in histological slides, a manual and time-consuming task that limits the ability to ...
arxiv  

Steroids in pediatric eosinophilic esophagitis [PDF]

, 2014
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
core   +1 more source